Fused functional-anatomic images of metastatic cancer of cervix obtained by a combined gamma camera and an X-ray tube hybrid system with an illustrative case and review of the 18F-fluorodeoxyglucose literature

18F-Fluorodeoxyglucose (FDG) assessments have provided clinically important information in cervical cancer. FDG studies can now be performed by both dedicated PET systems and by new-generation gamma cameras. Hybrid systems which consist of positron emission tomography (PET) or a gamma camera with X-...

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Bibliographic Details
Published in:Gynecologic oncology 2003-08, Vol.90 (2), p.453-457
Main Authors: Aizer-Dannon, Anat, Bar-Am, Amiram, Ron, Ilan G, Flusser, Gideon, Even-Sapir, Einat
Format: Article
Language:English
Subjects:
18F-Fluorodeoxyglucose
Biological and medical sciences
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - secondary
Cancer
Cervix
Endocrine glands. Genital system. Mammary gland
Female
Female genital diseases
Fluorine Radioisotopes
Fluorodeoxyglucose F18
Gamma camera
Gamma Cameras
Gynecology. Andrology. Obstetrics
Humans
Investigative techniques, diagnostic techniques (general aspects)
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - secondary
Lymph Nodes - diagnostic imaging
Lymph Nodes - pathology
Lymphatic Metastasis
Medical sciences
Middle Aged
PET
Radionuclide investigations
Radiopharmaceuticals
Tomography, Emission-Computed
Tumors
Uterine Cervical Neoplasms - diagnostic imaging
Uterine Cervical Neoplasms - pathology
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Summary:18F-Fluorodeoxyglucose (FDG) assessments have provided clinically important information in cervical cancer. FDG studies can now be performed by both dedicated PET systems and by new-generation gamma cameras. Hybrid systems which consist of positron emission tomography (PET) or a gamma camera with X-ray for fusion of functional-anatomic data without changing the patient’s position are now available. A woman with newly diagnosed cervical cancer underwent preoperative FDG studies using a hybrid gamma camera. In addition to the known primary tumor, FDG detected heretofore unidentified metastatic disease at the liver, bone, and para-aortic lymph nodes: the treatment approach was consequently altered to chemo- and radiotherapy. The fused images provided precise localization of the lesions, guiding bone biopsy and radiation field planning. When PET is unavailable, a modified gamma camera can provide clinically relevant data in patients with cervical cancer.
ISSN:0090-8258
1095-6859
DOI:10.1016/S0090-8258(03)00227-0