Mesenteric venous thrombosis in a patient with prothrombin 20210A mutation and antithrombin III deficiency: Challenges to conventional anticoagulation: A case report

Mesenteric venous thrombosis presents as vague abdominal pain in patients with a medical or family history suggestive of a hypercoagulable state. Classic computed tomography findings will often confirm the diagnosis, and the presence of persistent abdominal pain or tenderness will determine the need...

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Bibliographic Details
Published in:Vascular and endovascular surgery 2003-07, Vol.37 (4), p.293-296
Main Authors: JOHNSON, Chatt A, PARKER, Mary V, GOFF, James M
Format: Article
Language:English
Subjects:
Abdominal Pain - etiology
Adult
Anticoagulants (Medicine)
Anticoagulants - therapeutic use
Antithrombin III Deficiency - diagnosis
Antithrombin III Deficiency - drug therapy
Biological and medical sciences
Blood and lymphatic vessels
Blood clot
Cardiology. Vascular system
Care and treatment
Case studies
CT imaging
Diagnosis
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Drug use
Humans
Intestines - blood supply
Male
Management
Medical sciences
Mesenteric Vascular Occlusion - diagnosis
Mesenteric Vascular Occlusion - drug therapy
Mesenteric Veins - diagnostic imaging
Mesenteric Veins - pathology
Mutation - genetics
Prothrombin - analysis
Prothrombin - genetics
Thrombosis
Tomography, X-Ray Computed
Venous Thrombosis - diagnosis
Venous Thrombosis - drug therapy
Warfarin - therapeutic use
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Description
Summary:Mesenteric venous thrombosis presents as vague abdominal pain in patients with a medical or family history suggestive of a hypercoagulable state. Classic computed tomography findings will often confirm the diagnosis, and the presence of persistent abdominal pain or tenderness will determine the need for surgical intervention. Expeditious anticoagulation is the treatment of choice. This case demonstrates the CT findings for mesenteric venous thrombosis and discusses the challenges of anticoagulation in a patient with 2 hypercoagulable disorders.
ISSN:1538-5744
1938-9116
DOI:10.1177/153857440303700410