Pharmacologic treatment of binge eating disorder

Objective To review the findings from pharmacologic trials of binge eating disorder (BED) and to provide guidelines for pharmacologic treatment. Methods The literature was searched for studies of pharmacologic treatment of BED and related conditions, such as nonpurging bulimia nervosa. Results Place...

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Bibliographic Details
Published in:The International journal of eating disorders 2003, Vol.34 (S1), p.S74-S88
Main Authors: Carter, William P., Hudson, James I., Lalonde, Justine K., Pindyck, Lindsay, McElroy, Susan L., Pope Jr, Harrison G.
Format: Article
Language:English
Subjects:
anticonvulsants
Anticonvulsants - therapeutic use
antidepressants
Antidepressive Agents - therapeutic use
Appetite Depressants - therapeutic use
appetite suppressants
Binge eating
binge eating disorder
Bulimia
Bulimia - diagnosis
Bulimia - drug therapy
Bulimia - psychology
Drug therapy
Eating disorders
Humans
Pharmaceuticals
Pharmacology
Practice Guidelines as Topic
Randomized Controlled Trials as Topic
Serotonin Uptake Inhibitors - therapeutic use
Treatment Outcome
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Summary:Objective To review the findings from pharmacologic trials of binge eating disorder (BED) and to provide guidelines for pharmacologic treatment. Methods The literature was searched for studies of pharmacologic treatment of BED and related conditions, such as nonpurging bulimia nervosa. Results Placebo‐controlled studies of desipramine, fluvoxamine, fluoxetine, sertraline, citalopram, dexfenfluramine, sibutramine, and topiramate have demonstrated the efficacy of these agents in the treatment of BED. An open trial of venlafaxine has offered preliminary evidence for the efficacy of this medication. Guidelines for pharmacologic management of BED are provided. Conclusions The literature offers support for the use of agents from three categories of medication (antidepressants, appetite suppressants, and anticonvulsants) in the treatment of BED. © 2003 by Wiley Periodicals, Inc. Int J Eat Disord 34: S74–S88, 2003.
ISSN:0276-3478
1098-108X
DOI:10.1002/eat.10207