Cognitive, Behavioral, and Psychiatric Symptoms in Two Children with Agenesis of the Corpus Callosum: Case Report

Objective: To report two children, with normal intelligence, referred for evaluation of complex cognitive, behavioral, and psychiatric problems, in which Agenesis of Corpus Callosum (ACC) was an incidental finding. Method: Case descriptions are used and a comprehensive differential diagnosis made wi...

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Bibliographic Details
Published in:International journal of psychiatry in medicine 2003-01, Vol.33 (1), p.107-113
Main Authors: Párraga, Humberto C., Párraga, Marianela I., Jensen, Alicia R.
Format: Article
Language:English
Subjects:
Adult and adolescent clinical studies
Agenesis of Corpus Callosum
Attention deficit hyperactivity disorder
Behavior
Biological and medical sciences
Case reports
Child
Child & adolescent psychiatry
Child Behavior Disorders - complications
Child Behavior Disorders - diagnosis
Child Behavior Disorders - psychology
Cognition Disorders - complications
Cognition Disorders - diagnosis
Cognition Disorders - psychology
Corpus Callosum - physiopathology
Diagnosis, Differential
Electroencephalography
Female
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Organic mental disorders. Neuropsychology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
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Summary:Objective: To report two children, with normal intelligence, referred for evaluation of complex cognitive, behavioral, and psychiatric problems, in which Agenesis of Corpus Callosum (ACC) was an incidental finding. Method: Case descriptions are used and a comprehensive differential diagnosis made with previous diagnoses of partial complex seizures (PCS), psychosis, anxiety, attention deficit hyperactivity disorder (ADHD), and behavior disorder. Results: Due to the presence of multiple biopsychosocial interactions a multimodal intervention including pharmacological, behavioral, psychotherapeutic, and social approaches was implemented, with good results. Conclusion: These cases underscore the importance of conducting a comprehensive neuropsychiatric evaluation in children with severe behavior problems and other confusing symptoms. Since the incidence of ACC in behaviorally disturbed children, with normal intelligence, is unknown, physicians must accept that a reasonable degree of suspicion is warranted. Further studies are needed to facilitate physicians' awareness.
ISSN:0091-2174
1541-3527
DOI:10.2190/D4Y1-WNBX-HQW8-HDPL