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Synthesis and antimycobacterial activity of (3,4-diaryl-3 H-thiazol-2-ylidene)-hydrazide derivatives
[5-(Pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid (3,4-diaryl-3 H-thiazol-2-ylidene)-hydrazide derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed an interesting activity against a strain of Mycobacterium tuberculosis H 37Rv and three cl...
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| Published in: | Farmaco (Società chimica italiana : 1989) 2003-09, Vol.58 (9), p.631-637 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c306t-4a56f2a0258f5a09c00da757c745757beb32daeff929f36281821066d73902053 |
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| cites | cdi_FETCH-LOGICAL-c306t-4a56f2a0258f5a09c00da757c745757beb32daeff929f36281821066d73902053 |
| container_end_page | 637 |
| container_issue | 9 |
| container_start_page | 631 |
| container_title | Farmaco (Società chimica italiana : 1989) |
| container_volume | 58 |
| creator | Mamolo, Maria Grazia Falagiani, Valeria Zampieri, Daniele Vio, Luciano Banfi, Elena Scialino, Giuditta |
| description | [5-(Pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid (3,4-diaryl-3
H-thiazol-2-ylidene)-hydrazide derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed an interesting activity against a strain of
Mycobacterium tuberculosis H
37Rv and three clinical isolates of
M. tuberculosis. |
| doi_str_mv | 10.1016/S0014-827X(03)00103-4 |
| format | article |
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| identifier | ISSN: 0014-827X |
| ispartof | Farmaco (Società chimica italiana : 1989), 2003-09, Vol.58 (9), p.631-637 |
| issn | 0014-827X 1879-0569 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73566967 |
| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | 2-[5-(Pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid (3,4-diaryl-3 H-thiazol-2-ylidene)-hydrazide derivatives Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antimycobacterial activity Antitubercular Agents - chemical synthesis Antitubercular Agents - chemistry Antitubercular Agents - pharmacology Biological and medical sciences Hydrazines - chemical synthesis Hydrazines - chemistry Hydrazines - pharmacology Medical sciences Mycobacterium tuberculosis - drug effects Pharmacology. Drug treatments Structure-Activity Relationship Thiazoles - chemical synthesis Thiazoles - chemistry Thiazoles - pharmacology |
| title | Synthesis and antimycobacterial activity of (3,4-diaryl-3 H-thiazol-2-ylidene)-hydrazide derivatives |
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