Haploid allele mapping of Y-chromosome minisatellite, MSY1 (DYF155S1), to a Japanese population

The present study analyses the human Y-chromosome minisatellite locus, MSY1 (DYF155S1), in 205 Japanese males of 191 pedigrees using the minisatellite variant repeat (MVR) mapping system. The internal haploid structures of the detected alleles considerably varied and consisted of three major repeat...

Full description

Saved in:
Bibliographic Details
Published in:Legal medicine (Tokyo, Japan) Japan), 2003-06, Vol.5 (2), p.87-92
Main Authors: Jin, Zheng-Bin, Huang, Xiu-Lin, Nakajima, Yasuhiro, Yukawa, Nobuhiro, Osawa, Motoki, Takeichi, Sanae
Format: Article
Language:English
Subjects:
Alleles
Chromosomes, Human, Y - genetics
Haploidy
Humans
Japan
Male
Minisatellite
Minisatellite Repeats
Minisatellite variant repeat-polymerase chain reaction
MSY1 (DYF155S1)
Mutation
Paternity
Paternity test
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The present study analyses the human Y-chromosome minisatellite locus, MSY1 (DYF155S1), in 205 Japanese males of 191 pedigrees using the minisatellite variant repeat (MVR) mapping system. The internal haploid structures of the detected alleles considerably varied and consisted of three major repeat units: types 2, 3 and 4. A comparison of the haploid profiles of the MVR codes identified 185 distinct alleles, of which only five were shared. We did not detect a type 1 repeat unit, and variations were frequent at the 5′ end of the minisatellite locus. Within an analysis of 24 paternally linked DNA samples donated by ten families, no mutational events were identified even over two generation gaps. Furthermore, we applied this mapping system to a paternity test in which the alleged father was missing.
ISSN:1344-6223
1873-4162
DOI:10.1016/S1344-6223(03)00042-7