Ergonovine maleate test in various anginal syndromes

The ergonovine maleate (EM) test has been performed in four groups of 10 patients each: (A) variant angina; (B) angina at rest with ST segment depression during pain; (C) effort angina; (D) atypical chest i pain. EM was injected i.v. (highest dose 0-4 mg) first in the Coronary Care Unit and thereaft...

Full description

Saved in:
Bibliographic Details
Published in:European heart journal 1981-04, Vol.2 (2), p.139-146
Main Authors: MARESTA, A., CAPUCCI, A., MARZOCCHI, A., FERRETTI, R. M., PERTICUCCI, R., MAGNANI, B.
Format: Article
Language:English
Subjects:
Adult
angina
Angina Pectoris - diagnosis
Angina Pectoris - physiopathology
Blood Pressure
Coronary Angiography
coronary spasm
Electrocardiography
Ergonovine - analogs & derivatives
Ergonovine test
Female
Humans
Male
Middle Aged
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The ergonovine maleate (EM) test has been performed in four groups of 10 patients each: (A) variant angina; (B) angina at rest with ST segment depression during pain; (C) effort angina; (D) atypical chest i pain. EM was injected i.v. (highest dose 0-4 mg) first in the Coronary Care Unit and thereafter during coronary angiography. EM caused coronary spasm with angina and ST segment elevation in every patient of group A and in one patient of group B. In five and four patients of groups B and C, respectively, EM induced angina and ST segment depression without any localized coronary spasm, the coronary angiography showing only a diffuse narrowing of the coronary vessels; these patients had the lowest effort tolerance and the most severe coronary lesions. Spontaneous or induced coronary spasm in patients with angina at rest and ST segment depression during chest pain did not occur in this study. An increase of the peripheral and/or coronary resistances due to EM could be the mechanism of the ischemic attack in patients with severe coronary lesions.
ISSN:0195-668X
1522-9645
DOI:10.1093/oxfordjournals.eurheartj.a061174