Leiomyosarcoma of soft tissue: A clinicopathologic study

The case records and histologic material of 28 patients with leiomyosarcoma of soft tissue treated at M. D. Anderson Hospital between 1948 and 1975 were reviewed. These included patients in whom the tumors arose in the retroperitoneum (16), major blood vessels (3), and other soft‐tissue sites, colle...

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Bibliographic Details
Published in:Cancer 1981-08, Vol.48 (4), p.1022-1032
Main Authors: Wile, Alan G., Evans, Harry L., Romsdahl, Marvin M.
Format: Article
Language:English
Subjects:
Adult
Aged
Blood Vessels
Female
Follow-Up Studies
Humans
Leiomyosarcoma - pathology
Male
Middle Aged
Neoplasm Metastasis
Neoplasm Recurrence, Local - pathology
Prognosis
Retroperitoneal Neoplasms - pathology
Sex Factors
Soft Tissue Neoplasms - pathology
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Summary:The case records and histologic material of 28 patients with leiomyosarcoma of soft tissue treated at M. D. Anderson Hospital between 1948 and 1975 were reviewed. These included patients in whom the tumors arose in the retroperitoneum (16), major blood vessels (3), and other soft‐tissue sites, collectively designated peripheral soft tissue (9). Follow‐up was complete in all cases. A striking preponderance of female patients was observed in the group with retroperitoneal tumors, in contrast to the male preponderance in the vascular and peripheral soft tissue tumor groups. Tumor size and location were the major prognostic factors; large size (≥5 cm) and retroperitoneal origin were associated with a much poorer clinical outcome than smaller size (
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19810815)48:4<1022::AID-CNCR2820480429>3.0.CO;2-5