Enantiopure lanthanide complexes incorporating a tetraazatriphenylene sensitiser and three naphthyl groups: exciton coupling, intramolecular energy transfer, efficient singlet oxygen formation and perturbation by DNA binding

In cationic nine-coordinate chiral terbium and europium complexes incorporating exciton-coupled naphthyl groups and a tetraazatriphenylene sensitising chromophore, efficient intramolecular energy transfer occurs leading to population of the naphthyl triplet state. With the terbium complex, the absol...

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2003, Vol.1 (11), p.1870-1872
Main Authors: Bobba, Gabriella, Bretonnière, Yann, Frias, Juan-Carlos, Parker, David
Format: Article
Language:English
Subjects:
Animals
Cattle
Circular Dichroism
DNA - metabolism
DNA Probes - chemistry
Energy Transfer
Europium - chemistry
Europium - metabolism
Gadolinium - chemistry
Gadolinium - metabolism
Kinetics
Lanthanoid Series Elements - chemistry
Lanthanoid Series Elements - metabolism
Luminescent Measurements
Naphthalenes - chemistry
Naphthalenes - metabolism
Phenanthrolines - chemistry
Phenanthrolines - metabolism
Polyribonucleotides - chemistry
Polyribonucleotides - metabolism
Quantum Theory
Singlet Oxygen - chemistry
Spectrophotometry - methods
Stereoisomerism
Terbium - chemistry
Terbium - metabolism
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Summary:In cationic nine-coordinate chiral terbium and europium complexes incorporating exciton-coupled naphthyl groups and a tetraazatriphenylene sensitising chromophore, efficient intramolecular energy transfer occurs leading to population of the naphthyl triplet state. With the terbium complex, the absolute quantum yield of singlet oxygen formation is 51% (lambda(exc) 355 nm), and for the Eu complex the intensity of metal-based emission increases by up to 350% on binding to poly(dGdC) or calf-thymus DNA, and was greater for the delta-isomer.
ISSN:1477-0520
1477-0539
DOI:10.1039/b303085g