Estrogen receptor protein in breast cancer as a predictor of recurrence

Estrogen receptor protein (ERP) determinations of primary cancers of 1034 patients with primary breast cancer were done. ERP‐positive patients tended to have a lower recurrence rate and had significantly improved survival. This difference was most apparent in patients with four or more axillary node...

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Bibliographic Details
Published in:Cancer 1981-05, Vol.47 (10), p.2364-2367
Main Authors: Kinne, David W., Ashikari, Roy, Butler, Avital, Menendez‐Botet, Celia, Rosen, Paul Peter, Schwartz, Morton
Format: Article
Language:English
Subjects:
Breast Neoplasms - analysis
Breast Neoplasms - pathology
Breast Neoplasms - surgery
Female
Humans
Mastectomy
Middle Aged
Neoplasm Recurrence, Local
Probability
Prognosis
Receptors, Estrogen - analysis
Receptors, Progesterone - analysis
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Summary:Estrogen receptor protein (ERP) determinations of primary cancers of 1034 patients with primary breast cancer were done. ERP‐positive patients tended to have a lower recurrence rate and had significantly improved survival. This difference was most apparent in patients with four or more axillary nodes involved. ERP‐positive patients who recurred had a better survival. ERP did not influence response to adjuvant chemotherapy, nor did the presence of progesterone receptor or femtomole level of ERP affect recurrence.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19810515)47:10<2364::AID-CNCR2820471007>3.0.CO;2-S