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Intractable diarrhea: value of the small intestinal biopsy

In summarizing their article on intractable diarrhea of infancy Rossi et al1 stated, "a small bowel biopsy is useful in assessing the degree of injury present and guiding nutritional support." We concur that the small bowel biopsy is useful in assessing mucosal injury but has certain limit...

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Published in:Pediatrics (Evanston) 1981-09, Vol.68 (3), p.470-471
Main Authors: Byrne, W J, Euler, A R
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Language:English
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container_title Pediatrics (Evanston)
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creator Byrne, W J
Euler, A R
description In summarizing their article on intractable diarrhea of infancy Rossi et al1 stated, "a small bowel biopsy is useful in assessing the degree of injury present and guiding nutritional support." We concur that the small bowel biopsy is useful in assessing mucosal injury but has certain limitations. The authors used the Crosby-Krugler capsule, which obtains two small pieces of tissue, in close proximity. This limits the sensitivity of the technique as the specimens are not necessarily representative of the mucosal state of the entire small intestine nor do they allow exclusion of a patchy villous lesion.2
doi_str_mv 10.1542/peds.68.3.470a
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subjects Biopsy
Diarrhea, Infantile - pathology
Humans
Infant
Intestine, Small - pathology
title Intractable diarrhea: value of the small intestinal biopsy
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