Rapid Evolution of Male-Biased Gene Expression in Drosophila

A number of genes associated with sexual traits and reproduction evolve at the sequence level faster than the majority of genes coding for non-sex-related traits. Whole genome analyses allow this observation to be extended beyond the limited set of genes that have been studied thus far. We use cDNA...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 2003-08, Vol.100 (17), p.9894-9899
Main Authors: Meiklejohn, Colin D., Parsch, John, Ranz, José M., Hartl, Daniel L.
Format: Article
Language:English
Subjects:
Animals
Biological Evolution
Biological Sciences
Complementary DNA
Deoxyribonucleic acid
DNA
Drosophila
Drosophila - genetics
Drosophila melanogaster - genetics
Evolution
Evolutionary genetics
Female
Gender bias
Gene expression
Gene Expression Profiling
Genes
Genes, Insect
Genetic variation
Male
Male animals
Males
Oligonucleotide Array Sequence Analysis
Sex
Sex Characteristics
Species Specificity
Testes
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Summary:A number of genes associated with sexual traits and reproduction evolve at the sequence level faster than the majority of genes coding for non-sex-related traits. Whole genome analyses allow this observation to be extended beyond the limited set of genes that have been studied thus far. We use cDNA microarrays to demonstrate that this pattern holds in Drosophila for the phenotype of gene expression as well, but in one sex only. Genes that are male-biased in their expression show more variation in relative expression levels between conspecific populations and two closely related species than do female-biased genes or genes with sexually monomorphic expression patterns. Additionally, elevated ratios of interspecific expression divergence to intraspecific expression variation among male-biased genes suggest that differences in rates of evolution may be due in part to natural selection. This finding has implications for our understanding of the importance of sexual dimorphism for speciation and rates of phenotypic evolution.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.1630690100