In patients with severe systolic dysfunction, only brain natriuretic peptide is related to diastolic restrictive pattern

Background: In patients with severe systolic dysfunction the relationship between diastolic dysfunction and plasma levels of atrial and brain natriuretic peptide (ANP, BNP), catecholamines, renin, and aldosterone in patients with chronic heart failure (CHF) has never been investigated. Objectives: T...

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Bibliographic Details
Published in:Journal of cardiac failure 2003-08, Vol.9 (4), p.303-310
Main Authors: Catuzzo, Bruna, Ciancamerla, Francesca, Bobbio, Marco, Longo, Marcella, Trevi, Gian Paolo
Format: Article
Language:English
Subjects:
Adult
Aged
Aldosterone - blood
Area Under Curve
Biomarkers - blood
Blood Pressure - physiology
brain natriuretic peptide
Cardiomyopathies - blood
Cardiomyopathies - diagnosis
Cardiomyopathies - physiopathology
Chronic heart failure
Diastole - physiology
diastolic dysfunction
Echocardiography, Doppler
Epinephrine - blood
Female
Follow-Up Studies
Heart Failure - blood
Heart Failure - diagnosis
Heart Failure - physiopathology
Humans
Italy
Male
Middle Aged
Natriuretic Peptide, Brain - blood
neurohormonal activation
Norepinephrine - blood
Predictive Value of Tests
Prognosis
Quality of Life
Renin - blood
ROC Curve
Severity of Illness Index
Statistics as Topic
Stroke Volume - physiology
Systole - physiology
Ventricular Dysfunction, Left - blood
Ventricular Dysfunction, Left - diagnosis
Ventricular Dysfunction, Left - physiopathology
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Summary:Background: In patients with severe systolic dysfunction the relationship between diastolic dysfunction and plasma levels of atrial and brain natriuretic peptide (ANP, BNP), catecholamines, renin, and aldosterone in patients with chronic heart failure (CHF) has never been investigated. Objectives: The aim of this study was to evaluate in clinically stable patients with severe systolic dysfunction whether the presence of diastolic restrictive pattern modifies neurohormonal plasma levels. Methods: Of 82 consecutive patients with stable CHF, 36 were in sinus rhythm, had an adequate ultrasound window and an ejection fraction
ISSN:1071-9164
1532-8414
DOI:10.1054/jcaf.2003.44