Simple and Precise Preparation of a Porous Gel for a Colorimetric Glucose Sensor by a Templating Technique

Red for danger! A glucose‐sensitive gel is systematically prepared by careful control of the gel recipe to produce the desired swelling ratio at a given glucose concentration. Subsequently, a periodically ordered porous gel is obtained from the bulk gel by using a closest‐packing colloidal crystal a...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2003-09, Vol.42 (35), p.4197-4200
Main Authors: Nakayama, Daisuke, Takeoka, Yukikazu, Watanabe, Masayoshi, Kataoka, Kazunori
Format: Article
Language:English
Subjects:
Acrylamides - chemistry
Biosensing Techniques - methods
Boronic Acids - chemistry
colloids
Colloids - chemistry
Colorimetry
Gels - chemistry
Glucose - analysis
glucose sensors
Particle Size
polymers
Polymers - chemistry
porous gels
Silicon Dioxide - chemistry
Surface Properties
Temperature
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Summary:Red for danger! A glucose‐sensitive gel is systematically prepared by careful control of the gel recipe to produce the desired swelling ratio at a given glucose concentration. Subsequently, a periodically ordered porous gel is obtained from the bulk gel by using a closest‐packing colloidal crystal as a template; this template is subsequently removed. The gel exhibits expected structural color at certain glucose concentrations and thus can be used as a colorimetric glucose sensor, which may applied as a test for diabetes (see picture).
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200351746