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Galactosyltransferase Activities in Human Sera of Various Diseases

Recently galactosyltransferase has been noted as a new tumor marker. In this report galactosyltransferase activity was measured in sera of various diseases including malignant tumors and the levels of the enzyme activities were compared. The levels of the enzyme were higher in sera of malignant tumo...

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Published in:	RADIOISOTOPES 1981/03/15, Vol.30(3), pp.146-149
Main Authors:	MOTOKI, Tatsuya, KAWASE, Takeo, OHTA, Shin'ichi, TAKIGAWA, Hajime, SHIRATORI, Yasushi, KATAMOTO, Tetsuo, INAGAKI, Tohru, OKANO, Ken'ichi, TERANO, Akira, MATSUMOTO, Kazunori, MURAO, Satoru, NOMURA, Kijuro
Format:	Article
Language:	English
Subjects:	galactosyltransferase Galactosyltransferases - blood Humans liver disease Liver Diseases - enzymology malignant tumor Neoplasms - enzymology serum level tumor marker
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creator	MOTOKI, Tatsuya KAWASE, Takeo OHTA, Shin'ichi TAKIGAWA, Hajime SHIRATORI, Yasushi KATAMOTO, Tetsuo INAGAKI, Tohru OKANO, Ken'ichi TERANO, Akira MATSUMOTO, Kazunori MURAO, Satoru NOMURA, Kijuro
description	Recently galactosyltransferase has been noted as a new tumor marker. In this report galactosyltransferase activity was measured in sera of various diseases including malignant tumors and the levels of the enzyme activities were compared. The levels of the enzyme were higher in sera of malignant tumors and liver diseases than those in sera of other diseases. In malignant tumors little organ specificity was found with respect to the levels of galactosyltransferase activities. The levels of the enzyme were considered to have no relation to carcinoembryonic antigen or a feto protein. On the other hand, in liver diseases the levels of the enzyme were correlated to the severity of liver damage. Therefore, it is reasonable to presume that the elevation of serum galactosyltransferase activity is caused chiefly by malignant tumors and liver damage.
doi_str_mv	10.3769/radioisotopes.30.3_146
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subjects	galactosyltransferase Galactosyltransferases - blood Humans liver disease Liver Diseases - enzymology malignant tumor Neoplasms - enzymology serum level tumor marker
title	Galactosyltransferase Activities in Human Sera of Various Diseases
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