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Structure of the chicken apo very low density lipoprotein II gene
We describe two cloned genomic DNA fragments, both bearing the entire apo very low density lipoprotein II gene. Electron microscopy and restriction enzyme mapping showed that this gene is split into at least four coding sequences by three or more intervening sequences. A very short exon at the 5...
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Published in: | The Journal of biological chemistry 1981-09, Vol.256 (18), p.9668-9671 |
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container_end_page | 9671 |
container_issue | 18 |
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container_title | The Journal of biological chemistry |
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creator | Meijlink, F C van het Schip, A D Arnberg, A C Wieringa, B Ab, G Gruber, M |
description | We describe two cloned genomic DNA fragments, both bearing the entire apo very low density lipoprotein II gene. Electron microscopy
and restriction enzyme mapping showed that this gene is split into at least four coding sequences by three or more intervening
sequences. A very short exon at the 5'-end of the gene is separated by a 1.5-kilobase intron from the second exon, which codes
for the AUG initiation codon of the mRNA. |
doi_str_mv | 10.1016/S0021-9258(19)68814-9 |
format | article |
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and restriction enzyme mapping showed that this gene is split into at least four coding sequences by three or more intervening
sequences. A very short exon at the 5'-end of the gene is separated by a 1.5-kilobase intron from the second exon, which codes
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and restriction enzyme mapping showed that this gene is split into at least four coding sequences by three or more intervening
sequences. A very short exon at the 5'-end of the gene is separated by a 1.5-kilobase intron from the second exon, which codes
for the AUG initiation codon of the mRNA.</description><subject>Animals</subject><subject>Apolipoproteins - genetics</subject><subject>Chickens</subject><subject>DNA Restriction Enzymes</subject><subject>DNA, Recombinant - metabolism</subject><subject>Escherichia coli - genetics</subject><subject>Female</subject><subject>Genes</subject><subject>Lipoproteins, VLDL - genetics</subject><subject>Microscopy, Electron</subject><subject>Molecular Weight</subject><subject>Nucleic Acid Hybridization</subject><subject>Plasmids</subject><issn>0021-9258</issn><issn>1083-351X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><recordid>eNo9kFtLAzEQhYMoWqs_oRAQRB9WM9ndXB5L8VIo-KCCb2GTTN1ou1uTXcV_72qL8zID55w58BEyAXYFDMT1I2McMs1LdQH6UigFRab3yAiYyrO8hJd9Mvq3HJHjlN7YMIWGQ3IouGRMixGZPnaxd10fkbZL2tVIXR3cOza02rT0E-M3XbVf1GOTQjfcYdNuYtthaOh8Tl-xwRNysKxWCU93e0yeb2-eZvfZ4uFuPpsuMpdL3WVlZa2WHh1KZznTzCMoj7IAX6HgrgKrQEnrvAaRF94iB--EdQyZ5AXkY3K-_Tv0f_SYOrMOyeFqVTXY9snIXMhSaj4Yy63RxTaliEuziWFdxW8DzPyiM3_ozC8XA9r8oTN6yE12Bb1do_9P7VgN-tlWr8Nr_RUiGhtaV-Pa8FIYUEYLofIfO9t16A</recordid><startdate>19810925</startdate><enddate>19810925</enddate><creator>Meijlink, F C</creator><creator>van het Schip, A D</creator><creator>Arnberg, A C</creator><creator>Wieringa, B</creator><creator>Ab, G</creator><creator>Gruber, M</creator><general>American Society for Biochemistry and Molecular Biology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19810925</creationdate><title>Structure of the chicken apo very low density lipoprotein II gene</title><author>Meijlink, F C ; van het Schip, A D ; Arnberg, A C ; Wieringa, B ; Ab, G ; Gruber, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c379t-5abb97dece7cb2090de18de741dae62ca1b8187bcd91634dbe21dc6bc0e072413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Animals</topic><topic>Apolipoproteins - genetics</topic><topic>Chickens</topic><topic>DNA Restriction Enzymes</topic><topic>DNA, Recombinant - metabolism</topic><topic>Escherichia coli - genetics</topic><topic>Female</topic><topic>Genes</topic><topic>Lipoproteins, VLDL - genetics</topic><topic>Microscopy, Electron</topic><topic>Molecular Weight</topic><topic>Nucleic Acid Hybridization</topic><topic>Plasmids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Meijlink, F C</creatorcontrib><creatorcontrib>van het Schip, A D</creatorcontrib><creatorcontrib>Arnberg, A C</creatorcontrib><creatorcontrib>Wieringa, B</creatorcontrib><creatorcontrib>Ab, G</creatorcontrib><creatorcontrib>Gruber, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of biological chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Meijlink, F C</au><au>van het Schip, A D</au><au>Arnberg, A C</au><au>Wieringa, B</au><au>Ab, G</au><au>Gruber, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Structure of the chicken apo very low density lipoprotein II gene</atitle><jtitle>The Journal of biological chemistry</jtitle><addtitle>J Biol Chem</addtitle><date>1981-09-25</date><risdate>1981</risdate><volume>256</volume><issue>18</issue><spage>9668</spage><epage>9671</epage><pages>9668-9671</pages><issn>0021-9258</issn><eissn>1083-351X</eissn><abstract>We describe two cloned genomic DNA fragments, both bearing the entire apo very low density lipoprotein II gene. Electron microscopy
and restriction enzyme mapping showed that this gene is split into at least four coding sequences by three or more intervening
sequences. A very short exon at the 5'-end of the gene is separated by a 1.5-kilobase intron from the second exon, which codes
for the AUG initiation codon of the mRNA.</abstract><cop>United States</cop><pub>American Society for Biochemistry and Molecular Biology</pub><pmid>6270096</pmid><doi>10.1016/S0021-9258(19)68814-9</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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source | ScienceDirect Journals |
subjects | Animals Apolipoproteins - genetics Chickens DNA Restriction Enzymes DNA, Recombinant - metabolism Escherichia coli - genetics Female Genes Lipoproteins, VLDL - genetics Microscopy, Electron Molecular Weight Nucleic Acid Hybridization Plasmids |
title | Structure of the chicken apo very low density lipoprotein II gene |
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