Effects of Ethanol on Urinary Arginine Vasopressin Excretion in Two Rat Strains Selected for Their Different Ethanol Preferences

The effects of ethanol on urinary excretion of arginine vasopressin (AVP), sodium, and potassium were investigated in two rat strains specially selected for their different alcohol preferences. The alcohol preferring (AA) strain excreted more AVP and the water preferring (ANA) strain more urine and...

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Bibliographic Details
Published in:Acta physiologica Scandinavica 1977-09, Vol.101 (1), p.126-128
Main Authors: Linkola, Jaakko, Fyhrquist, Frej, Forsander, Olof
Format: Article
Language:English
Subjects:
Animals
Arginine Vasopressin - urine
Ethanol - pharmacology
Female
Male
Potassium - urine
Rats
Rats, Inbred Strains
Sodium - urine
Vasopressins - analogs & derivatives
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Summary:The effects of ethanol on urinary excretion of arginine vasopressin (AVP), sodium, and potassium were investigated in two rat strains specially selected for their different alcohol preferences. The alcohol preferring (AA) strain excreted more AVP and the water preferring (ANA) strain more urine and sodium during six hours after ethanol intubation (2.4 g/kg b.w.; 20% v/v). The data is insufficient to establish a causal relationship between differences in water and electrolyte metabolism and voluntary ethanol consumption.
ISSN:0001-6772
1365-201X
DOI:10.1111/j.1748-1716.1977.tb05991.x