Establishment of a Cell Line with Associated Epstein-Barr-Like Virus from a Leukemic Orangutan

An Epstein-Barr virus like herpesvirus has been isolated from a lymphoid cell line derived from an orangutan with spontaneous myelomonocytic leukemia. Herpesvirus has not previously been isolated from this species of higher ape.

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1977-10, Vol.198 (4315), p.407-409
Main Authors: Rasheed, Suraiya, Rongey, Robert W., Bruszweski, Joan, Nelson-Rees, Walter A., Rabin, Harvey, Neubauer, Russell H., Esra, Gerald, Gardner, Murray B.
Format: Article
Language:English
Subjects:
Amino acids
Animals
Antigens, Viral - analysis
Blood cells
Cell Line
Cell lines
Chromosomes
Erythrocytes
Herpesviridae
Herpesviridae - isolation & purification
Herpesvirus 4, Human - immunology
Hominidae - microbiology
Inclusion Bodies, Viral
Karyotyping
Leukemia
Leukemia, Myeloid - genetics
Leukemia, Myeloid - microbiology
Leukemia, Myeloid - veterinary
Leukocytes - microbiology
Orangutans
Stem cells
Viruses
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Description
Summary:An Epstein-Barr virus like herpesvirus has been isolated from a lymphoid cell line derived from an orangutan with spontaneous myelomonocytic leukemia. Herpesvirus has not previously been isolated from this species of higher ape.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.198878