The spread of cancer in the organism. Facts and problems

In this review, cancer is conceived as an alteration of the suface-monitored social behavior of cells. Apart from impaired growth controls, loss of residency (tissue affiliation) is the most important consequence of this homeostatic disorder. It results in local spread (penetration) which is initiat...

Full description

Saved in:
Bibliographic Details
Published in:Die Naturwissenschaften 1977-08, Vol.64 (8), p.403-409
Main Author: Str uli, P.
Format: Article
Language:English
Subjects:
Animals
Cell Adhesion
Cell Movement
Humans
Lymph Nodes - physiopathology
Microscopy, Electron, Scanning
Neoplasm Metastasis
Neoplasms - physiopathology
Neoplasms, Experimental - physiopathology
Sarcoma, Experimental - physiopathology
Sarcoma, Experimental - ultrastructure
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this review, cancer is conceived as an alteration of the suface-monitored social behavior of cells. Apart from impaired growth controls, loss of residency (tissue affiliation) is the most important consequence of this homeostatic disorder. It results in local spread (penetration) which is initiated by locomotive and/or desctructive activities of the neoplastic cells. Access of cancer elements to the circulation possibly leads to distant spread (metastasis). Penetration and metastasis largely depend upon reactions of the organism, which are of an ill-understood, ambiguous nature favoring both the tumor and the host.
ISSN:0028-1042
1432-1904
DOI:10.1007/BF00508691