Low cholesterol level in patients with panic disorder: the association with major depression

Background: The purpose of this study was to examine whether an association exists between low cholesterol level and major depression in patients with panic disorder. Methods: The subjects of the study were 16 patients panic disorder only, 16 panic disorder patients had also current major depressive...

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Bibliographic Details
Published in:Journal of affective disorders 1998-07, Vol.50 (1), p.29-32
Main Authors: Agargün, Mehmed Yücel, Algün, Ekrem, Şekeroğlu, Ramazan, Kara, Hayrettin, Tarakçioğlu, Mehmed
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Anxiety disorders. Neuroses
Biological and medical sciences
Cholesterol
Cholesterol - blood
Depressive Disorder - blood
Depressive Disorder - complications
Female
Humans
Major depression
Male
Medical sciences
Middle Aged
Panic disorder
Panic Disorder - blood
Panic Disorder - complications
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
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Summary:Background: The purpose of this study was to examine whether an association exists between low cholesterol level and major depression in patients with panic disorder. Methods: The subjects of the study were 16 patients panic disorder only, 16 panic disorder patients had also current major depressive episode, and 16 normal control subjects. An automated enzymatic colorimetric method was used for cholesterol determination. Results: Panic disorder patients had higher serum cholesterol than panic disorder patients with major depression and normal controls. Conclusion: There is an association between low cholesterol level and the presence of major depression in patients with panic disorder. Limitation: Future studies with large sample are needed to confirm this finding. Clinical Relevance: A low serum cholesterol level might serve as biological marker of major depression in patients panic disorder.
ISSN:0165-0327
1573-2517
DOI:10.1016/S0165-0327(97)00194-8