Analysis of CD34-Expressing Cells in Clinical Practice

The flow cytometric determination of haemopoietic cells defined as CD34‐ expressing cells has greatly added to the improvement of the management of harvesting circulating haemopoietic cells for subsequent autologous reinfusion in the setting of high‐dose chemo/(radio)‐therapy. Additionally, this flo...

Full description

Saved in:
Bibliographic Details
Published in:Vox sanguinis 1998-06, Vol.74 (S2), p.469-475
Main Authors: Serke, S., Beyer, J., Rick, O., Schwella, N., Meyer, O., Hildebrandt, M., Huhn, D.
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Antigens, CD34 - analysis
Antigens, Differentiation - analysis
Apoptosis
Biological and medical sciences
Body Weight
Bone marrow, stem cells transplantation. Graft versus host reaction
Cell Count - instrumentation
Cell Count - methods
Cell Separation
Colony-Forming Units Assay
Flow Cytometry
Graft Survival
Hematopoietic Stem Cell Transplantation - methods
Hematopoietic Stem Cells - cytology
Humans
Medical sciences
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The flow cytometric determination of haemopoietic cells defined as CD34‐ expressing cells has greatly added to the improvement of the management of harvesting circulating haemopoietic cells for subsequent autologous reinfusion in the setting of high‐dose chemo/(radio)‐therapy. Additionally, this flow cytometric determination has replaced, in some institutions, the in‐vitro culture test for CFU‐GM as the measure to estimate the haemopoietic potential of the cells to be reinfused/transplanted.
ISSN:0042-9007
1423-0410
DOI:10.1111/j.1423-0410.1998.tb05459.x