The DF-1 Chicken Fibroblast Cell Line: Transformation Induced by Diverse Oncogenes and Cell Death Resulting from Infection by Avian Leukosis Viruses

DF-1 is a continuous cell line of chicken embryo fibroblasts. The cells are free of endogenous sequences related to avian sarcoma and leukosis viruses and have normal fibroblastic morphology. DF-1 cells support the replication of avian retroviruses; diverse oncogenes induce foci of oncogenic transfo...

Full description

Saved in:
Bibliographic Details
Published in:Virology (New York, N.Y.) N.Y.), 1998-09, Vol.248 (2), p.295-304
Main Authors: Himly, Martin, Foster, Douglas N., Bottoli, Ivan, Iacovoni, Jason S., Vogt, Peter K.
Format: Article
Language:English
Subjects:
Animals
Avian leukosis virus
Avian Leukosis Virus - physiology
Cell Death
Cell Line - physiology
Cell Line - virology
Cell Transformation, Neoplastic
Cells, Cultured
Chick Embryo
Chickens
Fibroblasts - physiology
Fibroblasts - virology
Genes, jun - physiology
Oncogenes - physiology
Virus Replication
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c476t-75fb222422d25f587784b50fb2435136ef8f4c2a129317552785b754dd1437ca3
cites cdi_FETCH-LOGICAL-c476t-75fb222422d25f587784b50fb2435136ef8f4c2a129317552785b754dd1437ca3
container_end_page 304
container_issue 2
container_start_page 295
container_title Virology (New York, N.Y.)
container_volume 248
creator Himly, Martin
Foster, Douglas N.
Bottoli, Ivan
Iacovoni, Jason S.
Vogt, Peter K.
description DF-1 is a continuous cell line of chicken embryo fibroblasts. The cells are free of endogenous sequences related to avian sarcoma and leukosis viruses and have normal fibroblastic morphology. DF-1 cells support the replication of avian retroviruses; diverse oncogenes induce foci of oncogenic transformation on monolayers of DF-1, and avian leukosis viruses of envelope subgroups B, D, and C induce cell death and form plaques. The new cell line will greatly facilitate studies on oncogenic transformation and cell killing by avian viruses.
doi_str_mv 10.1006/viro.1998.9290
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73855243</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S004268229899290X</els_id><sourcerecordid>73855243</sourcerecordid><originalsourceid>FETCH-LOGICAL-c476t-75fb222422d25f587784b50fb2435136ef8f4c2a129317552785b754dd1437ca3</originalsourceid><addsrcrecordid>eNqFkc1uEzEUhS0EKmlhyw7JK3YT_Dv2sKsSUipFqoTSbi2P505jOmMXeyZS34MHxiERO8TKur7nHF2dD6EPlCwpIfXng09xSZtGLxvWkFdoQUlTV4QL-hotCBGsqjVjb9Flzj9ImZUiF-iiUYwyrhfo124PeL2pKF7tvXuCgDe-TbEdbJ7wCoYBb32AL3iXbMh9TKOdfAz4NnSzgw63L3jtD5Ay4Lvg4iMEyNiG7mRdg532-DvkeZh8eMR9imOx9uD-hBTz9cHbgLcwP8XsM37wac6Q36E3vR0yvD-_V-h-83W3-lZt725uV9fbyglVT5WSfcsYE4x1TPZSK6VFK0n5FFxSXkOve-GYpazhVEnJlJatkqLrqODKWX6FPp1yn1P8OUOezOizK5fbAHHORnFdXIL_V0gVLXcIUoTLk9ClmHOC3jwnP9r0YigxR17myMsceZkjr2L4eE6e2xG6v_IzoLLXpz2UHg4eksnOQyjd-1RqNF30_4r-DcutpBM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>17122440</pqid></control><display><type>article</type><title>The DF-1 Chicken Fibroblast Cell Line: Transformation Induced by Diverse Oncogenes and Cell Death Resulting from Infection by Avian Leukosis Viruses</title><source>Elsevier</source><creator>Himly, Martin ; Foster, Douglas N. ; Bottoli, Ivan ; Iacovoni, Jason S. ; Vogt, Peter K.</creator><creatorcontrib>Himly, Martin ; Foster, Douglas N. ; Bottoli, Ivan ; Iacovoni, Jason S. ; Vogt, Peter K.</creatorcontrib><description>DF-1 is a continuous cell line of chicken embryo fibroblasts. The cells are free of endogenous sequences related to avian sarcoma and leukosis viruses and have normal fibroblastic morphology. DF-1 cells support the replication of avian retroviruses; diverse oncogenes induce foci of oncogenic transformation on monolayers of DF-1, and avian leukosis viruses of envelope subgroups B, D, and C induce cell death and form plaques. The new cell line will greatly facilitate studies on oncogenic transformation and cell killing by avian viruses.</description><identifier>ISSN: 0042-6822</identifier><identifier>EISSN: 1096-0341</identifier><identifier>DOI: 10.1006/viro.1998.9290</identifier><identifier>PMID: 9721238</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Avian leukosis virus ; Avian Leukosis Virus - physiology ; Cell Death ; Cell Line - physiology ; Cell Line - virology ; Cell Transformation, Neoplastic ; Cells, Cultured ; Chick Embryo ; Chickens ; Fibroblasts - physiology ; Fibroblasts - virology ; Genes, jun - physiology ; Oncogenes - physiology ; Virus Replication</subject><ispartof>Virology (New York, N.Y.), 1998-09, Vol.248 (2), p.295-304</ispartof><rights>1998 Academic Press</rights><rights>Copyright 1998 Academic Press.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c476t-75fb222422d25f587784b50fb2435136ef8f4c2a129317552785b754dd1437ca3</citedby><cites>FETCH-LOGICAL-c476t-75fb222422d25f587784b50fb2435136ef8f4c2a129317552785b754dd1437ca3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9721238$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Himly, Martin</creatorcontrib><creatorcontrib>Foster, Douglas N.</creatorcontrib><creatorcontrib>Bottoli, Ivan</creatorcontrib><creatorcontrib>Iacovoni, Jason S.</creatorcontrib><creatorcontrib>Vogt, Peter K.</creatorcontrib><title>The DF-1 Chicken Fibroblast Cell Line: Transformation Induced by Diverse Oncogenes and Cell Death Resulting from Infection by Avian Leukosis Viruses</title><title>Virology (New York, N.Y.)</title><addtitle>Virology</addtitle><description>DF-1 is a continuous cell line of chicken embryo fibroblasts. The cells are free of endogenous sequences related to avian sarcoma and leukosis viruses and have normal fibroblastic morphology. DF-1 cells support the replication of avian retroviruses; diverse oncogenes induce foci of oncogenic transformation on monolayers of DF-1, and avian leukosis viruses of envelope subgroups B, D, and C induce cell death and form plaques. The new cell line will greatly facilitate studies on oncogenic transformation and cell killing by avian viruses.</description><subject>Animals</subject><subject>Avian leukosis virus</subject><subject>Avian Leukosis Virus - physiology</subject><subject>Cell Death</subject><subject>Cell Line - physiology</subject><subject>Cell Line - virology</subject><subject>Cell Transformation, Neoplastic</subject><subject>Cells, Cultured</subject><subject>Chick Embryo</subject><subject>Chickens</subject><subject>Fibroblasts - physiology</subject><subject>Fibroblasts - virology</subject><subject>Genes, jun - physiology</subject><subject>Oncogenes - physiology</subject><subject>Virus Replication</subject><issn>0042-6822</issn><issn>1096-0341</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><recordid>eNqFkc1uEzEUhS0EKmlhyw7JK3YT_Dv2sKsSUipFqoTSbi2P505jOmMXeyZS34MHxiERO8TKur7nHF2dD6EPlCwpIfXng09xSZtGLxvWkFdoQUlTV4QL-hotCBGsqjVjb9Flzj9ImZUiF-iiUYwyrhfo124PeL2pKF7tvXuCgDe-TbEdbJ7wCoYBb32AL3iXbMh9TKOdfAz4NnSzgw63L3jtD5Ay4Lvg4iMEyNiG7mRdg532-DvkeZh8eMR9imOx9uD-hBTz9cHbgLcwP8XsM37wac6Q36E3vR0yvD-_V-h-83W3-lZt725uV9fbyglVT5WSfcsYE4x1TPZSK6VFK0n5FFxSXkOve-GYpazhVEnJlJatkqLrqODKWX6FPp1yn1P8OUOezOizK5fbAHHORnFdXIL_V0gVLXcIUoTLk9ClmHOC3jwnP9r0YigxR17myMsceZkjr2L4eE6e2xG6v_IzoLLXpz2UHg4eksnOQyjd-1RqNF30_4r-DcutpBM</recordid><startdate>19980901</startdate><enddate>19980901</enddate><creator>Himly, Martin</creator><creator>Foster, Douglas N.</creator><creator>Bottoli, Ivan</creator><creator>Iacovoni, Jason S.</creator><creator>Vogt, Peter K.</creator><general>Elsevier Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19980901</creationdate><title>The DF-1 Chicken Fibroblast Cell Line: Transformation Induced by Diverse Oncogenes and Cell Death Resulting from Infection by Avian Leukosis Viruses</title><author>Himly, Martin ; Foster, Douglas N. ; Bottoli, Ivan ; Iacovoni, Jason S. ; Vogt, Peter K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c476t-75fb222422d25f587784b50fb2435136ef8f4c2a129317552785b754dd1437ca3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Animals</topic><topic>Avian leukosis virus</topic><topic>Avian Leukosis Virus - physiology</topic><topic>Cell Death</topic><topic>Cell Line - physiology</topic><topic>Cell Line - virology</topic><topic>Cell Transformation, Neoplastic</topic><topic>Cells, Cultured</topic><topic>Chick Embryo</topic><topic>Chickens</topic><topic>Fibroblasts - physiology</topic><topic>Fibroblasts - virology</topic><topic>Genes, jun - physiology</topic><topic>Oncogenes - physiology</topic><topic>Virus Replication</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Himly, Martin</creatorcontrib><creatorcontrib>Foster, Douglas N.</creatorcontrib><creatorcontrib>Bottoli, Ivan</creatorcontrib><creatorcontrib>Iacovoni, Jason S.</creatorcontrib><creatorcontrib>Vogt, Peter K.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Virology (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Himly, Martin</au><au>Foster, Douglas N.</au><au>Bottoli, Ivan</au><au>Iacovoni, Jason S.</au><au>Vogt, Peter K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The DF-1 Chicken Fibroblast Cell Line: Transformation Induced by Diverse Oncogenes and Cell Death Resulting from Infection by Avian Leukosis Viruses</atitle><jtitle>Virology (New York, N.Y.)</jtitle><addtitle>Virology</addtitle><date>1998-09-01</date><risdate>1998</risdate><volume>248</volume><issue>2</issue><spage>295</spage><epage>304</epage><pages>295-304</pages><issn>0042-6822</issn><eissn>1096-0341</eissn><abstract>DF-1 is a continuous cell line of chicken embryo fibroblasts. The cells are free of endogenous sequences related to avian sarcoma and leukosis viruses and have normal fibroblastic morphology. DF-1 cells support the replication of avian retroviruses; diverse oncogenes induce foci of oncogenic transformation on monolayers of DF-1, and avian leukosis viruses of envelope subgroups B, D, and C induce cell death and form plaques. The new cell line will greatly facilitate studies on oncogenic transformation and cell killing by avian viruses.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>9721238</pmid><doi>10.1006/viro.1998.9290</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0042-6822
ispartof Virology (New York, N.Y.), 1998-09, Vol.248 (2), p.295-304
issn 0042-6822
1096-0341
language eng
recordid cdi_proquest_miscellaneous_73855243
source Elsevier
subjects Animals
Avian leukosis virus
Avian Leukosis Virus - physiology
Cell Death
Cell Line - physiology
Cell Line - virology
Cell Transformation, Neoplastic
Cells, Cultured
Chick Embryo
Chickens
Fibroblasts - physiology
Fibroblasts - virology
Genes, jun - physiology
Oncogenes - physiology
Virus Replication
title The DF-1 Chicken Fibroblast Cell Line: Transformation Induced by Diverse Oncogenes and Cell Death Resulting from Infection by Avian Leukosis Viruses
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T21%3A52%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20DF-1%20Chicken%20Fibroblast%20Cell%20Line:%20Transformation%20Induced%20by%20Diverse%20Oncogenes%20and%20Cell%20Death%20Resulting%20from%20Infection%20by%20Avian%20Leukosis%20Viruses&rft.jtitle=Virology%20(New%20York,%20N.Y.)&rft.au=Himly,%20Martin&rft.date=1998-09-01&rft.volume=248&rft.issue=2&rft.spage=295&rft.epage=304&rft.pages=295-304&rft.issn=0042-6822&rft.eissn=1096-0341&rft_id=info:doi/10.1006/viro.1998.9290&rft_dat=%3Cproquest_cross%3E73855243%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c476t-75fb222422d25f587784b50fb2435136ef8f4c2a129317552785b754dd1437ca3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=17122440&rft_id=info:pmid/9721238&rfr_iscdi=true