Antihyperlipidemic effect of hydroalcoholic extract, and polyphenolic fraction from Dracocephalum kotschyi Boiss

Blood lipid levels in rats with hyperlipidemia resulting from high-fat feeding were determined after oral administration of hydroalcoholic extract and polyphenolic fraction of Dracocephalum kotschyi leaves. Administration of the hydroalcoholic extract and polyphenolic fraction produced a significant...

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Bibliographic Details
Published in:Pharmaceutica acta Helvetiae 1998-08, Vol.73 (3), p.167-170
Main Authors: Ebrahim Sajjadi, S, Movahedian Atar, A, Yektaian, A
Format: Article
Language:English
Subjects:
Administration, Oral
Animals
Antihyperlipidemic effect
Biological and medical sciences
Dracocephalum kotschyi
Flavonoids
General pharmacology
Hypolipidemic Agents - chemistry
Hypolipidemic Agents - pharmacology
Lamiaceae
Lipids - blood
Male
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phenols
Plant Extracts - administration & dosage
Plant Extracts - chemistry
Plant Extracts - pharmacology
Polymers
Polyphenols
Rats
Rats, Wistar
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Summary:Blood lipid levels in rats with hyperlipidemia resulting from high-fat feeding were determined after oral administration of hydroalcoholic extract and polyphenolic fraction of Dracocephalum kotschyi leaves. Administration of the hydroalcoholic extract and polyphenolic fraction produced a significant decrease of blood triglyceride, total cholesterol and LDL-cholesterol levels. HDL-cholesterol level was significantly increased.
ISSN:0031-6865
DOI:10.1016/S0031-6865(98)00016-8