Left ventricular diastolic filling in the elderly: the cardiovascular health study

Changes in left ventricular (LV) diastolic function (e.g., as measured by transmitral flow velocity) are known to occur with aging. In addition, impaired LV diastolic function plays an important role in such cardiovascular disorders common in the elderly as hypertension, ischemic heart disease, and...

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Bibliographic Details
Published in:The American journal of cardiology 1998-08, Vol.82 (3), p.345-351
Main Authors: Gardin, Julius M, Arnold, Alice M, Bild, Diane E, Smith, Vivienne-Elizabeth, Lima, Joao A.C, Klopfenstein, H.Sidney, Kitzman, Dalane W
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Analysis of Variance
Biological and medical sciences
Blood Flow Velocity
Cardiology. Vascular system
Cardiovascular disease
Cardiovascular Diseases - diagnostic imaging
Cardiovascular Diseases - physiopathology
Cohort Studies
Diastole
Echocardiography, Doppler
Electrocardiography
Female
Health Status
Heart
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Heart Ventricles - diagnostic imaging
Heart Ventricles - physiopathology
Humans
Male
Medical sciences
Older people
Ventricular Function, Left - physiology
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Summary:Changes in left ventricular (LV) diastolic function (e.g., as measured by transmitral flow velocity) are known to occur with aging. In addition, impaired LV diastolic function plays an important role in such cardiovascular disorders common in the elderly as hypertension, ischemic heart disease, and congestive heart failure (CHF). Participants in the Cardiovascular Health Study, a multicenter study of community-dwelling men (n = 2,239) and women (n = 2,962) ≥65 years of age, underwent an extensive baseline evaluation, including echocardiography. Early diastolic LV Doppler (transmitral) peak filling velocity decreased, and peak late diastolic (atrial) velocity increased with age in multivariate analyses (all p
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(98)00339-7