Immunohistochemical Localization of Renin in Luteinizing Hormone-Producing Cells of Rat Pituitary

The location of renin (EC 3.4.99.19) in rat pituitary was determined by the peroxidase-antiperoxidase immunohistochemical technique. By using antisera prepared with purified rat renal renin, an immunoreactive substance was localized within ovoid cells scattered throughout the anterior pituitary. The...

Full description

Saved in:
Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 1981-12, Vol.78 (12), p.7579-7583
Main Authors: Naruse, Kiyoko, Takii, Yukio, Inagami, Tadashi
Format: Article
Language:English
Subjects:
Adrenocorticotropic Hormone - metabolism
Animals
Anterior pituitary
Antibodies
Antigens
Antiserum
Cells
Cellular immunity
Growth Hormone - metabolism
Hormones
Immunoenzyme Techniques
Luteinization
Luteinizing Hormone - biosynthesis
Male
Pituitary Gland, Anterior - cytology
Pituitary Gland, Anterior - metabolism
Prolactin - metabolism
Rats
Rats, Inbred Strains
Renin - metabolism
Sheep
Thyrotropin - metabolism
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c527t-43368ce0b6296385f251fc39cb2baaf6ceab231ea501b827b0da6d76834dc4ff3
cites
container_end_page 7583
container_issue 12
container_start_page 7579
container_title Proceedings of the National Academy of Sciences - PNAS
container_volume 78
creator Naruse, Kiyoko
Takii, Yukio
Inagami, Tadashi
description The location of renin (EC 3.4.99.19) in rat pituitary was determined by the peroxidase-antiperoxidase immunohistochemical technique. By using antisera prepared with purified rat renal renin, an immunoreactive substance was localized within ovoid cells scattered throughout the anterior pituitary. These cells were shown to be luteinizing hormone-producing cells by staining with anti-luteinizing hormone antisera in adjacent sections. By using the double staining method, the renin-containing cells were differentiated from cells containing corticotropin, thyrotropin, growth hormone (somatotropin), and prolactin (mammotropin). These results suggest a possible local role for renin in the anterior pituitary.
doi_str_mv 10.1073/pnas.78.12.7579
format article
fullrecord <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_73880732</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>11245</jstor_id><sourcerecordid>11245</sourcerecordid><originalsourceid>FETCH-LOGICAL-c527t-43368ce0b6296385f251fc39cb2baaf6ceab231ea501b827b0da6d76834dc4ff3</originalsourceid><addsrcrecordid>eNp9kc1LHDEYxoO02PXjLAiWOelp1nzNJHPooSxahYWK6DlkMokbmUnWJFOqf72Z7qrtpRASyPN73vdNHgCOEJwjyMj52sk4Z3yO8JxVrNkBMwQbVNa0gZ_ADELMSk4x_QL2YnyEEDYVh7tgt8aMUw5nQF4Pw-j8ysbk1UoPVsm-WPq82xeZrHeFN8WtdtYVeS3HpK2zL9Y9FFc-DN7p8ib4blTTzUL3ffzDy1Tc2DTaJMPzAfhsZB_14fbcB_eXF3eLq3L588f14vuyVBVmqaSE1Fxp2Na4qQmvDK6QUaRRLW6lNLXSssUEaVlB1HLMWtjJumM1J7RT1BiyD75t6q7HdtCd0i4F2Yt1sEOeQnhpxb-Ksyvx4H8JQhuCcPafbv3BP406JjHYqPKTpNN-jIIRzvOPT-D5BlTBxxi0ee-BoJhCEVMognGBsJhCyY6Tv0d757cpZP1sq0_GN_WjgDBj3yf9O2Xy63_JDBxvgMccaPiYDGFakVdNdKzG</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73880732</pqid></control><display><type>article</type><title>Immunohistochemical Localization of Renin in Luteinizing Hormone-Producing Cells of Rat Pituitary</title><source>Open Access: PubMed Central</source><source>JSTOR Archival Journals and Primary Sources Collection</source><creator>Naruse, Kiyoko ; Takii, Yukio ; Inagami, Tadashi</creator><creatorcontrib>Naruse, Kiyoko ; Takii, Yukio ; Inagami, Tadashi</creatorcontrib><description>The location of renin (EC 3.4.99.19) in rat pituitary was determined by the peroxidase-antiperoxidase immunohistochemical technique. By using antisera prepared with purified rat renal renin, an immunoreactive substance was localized within ovoid cells scattered throughout the anterior pituitary. These cells were shown to be luteinizing hormone-producing cells by staining with anti-luteinizing hormone antisera in adjacent sections. By using the double staining method, the renin-containing cells were differentiated from cells containing corticotropin, thyrotropin, growth hormone (somatotropin), and prolactin (mammotropin). These results suggest a possible local role for renin in the anterior pituitary.</description><identifier>ISSN: 0027-8424</identifier><identifier>EISSN: 1091-6490</identifier><identifier>DOI: 10.1073/pnas.78.12.7579</identifier><identifier>PMID: 6278480</identifier><language>eng</language><publisher>United States: National Academy of Sciences of the United States of America</publisher><subject>Adrenocorticotropic Hormone - metabolism ; Animals ; Anterior pituitary ; Antibodies ; Antigens ; Antiserum ; Cells ; Cellular immunity ; Growth Hormone - metabolism ; Hormones ; Immunoenzyme Techniques ; Luteinization ; Luteinizing Hormone - biosynthesis ; Male ; Pituitary Gland, Anterior - cytology ; Pituitary Gland, Anterior - metabolism ; Prolactin - metabolism ; Rats ; Rats, Inbred Strains ; Renin - metabolism ; Sheep ; Thyrotropin - metabolism</subject><ispartof>Proceedings of the National Academy of Sciences - PNAS, 1981-12, Vol.78 (12), p.7579-7583</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c527t-43368ce0b6296385f251fc39cb2baaf6ceab231ea501b827b0da6d76834dc4ff3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://www.pnas.org/content/78/12.cover.gif</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/11245$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/11245$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793,58238,58471</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6278480$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Naruse, Kiyoko</creatorcontrib><creatorcontrib>Takii, Yukio</creatorcontrib><creatorcontrib>Inagami, Tadashi</creatorcontrib><title>Immunohistochemical Localization of Renin in Luteinizing Hormone-Producing Cells of Rat Pituitary</title><title>Proceedings of the National Academy of Sciences - PNAS</title><addtitle>Proc Natl Acad Sci U S A</addtitle><description>The location of renin (EC 3.4.99.19) in rat pituitary was determined by the peroxidase-antiperoxidase immunohistochemical technique. By using antisera prepared with purified rat renal renin, an immunoreactive substance was localized within ovoid cells scattered throughout the anterior pituitary. These cells were shown to be luteinizing hormone-producing cells by staining with anti-luteinizing hormone antisera in adjacent sections. By using the double staining method, the renin-containing cells were differentiated from cells containing corticotropin, thyrotropin, growth hormone (somatotropin), and prolactin (mammotropin). These results suggest a possible local role for renin in the anterior pituitary.</description><subject>Adrenocorticotropic Hormone - metabolism</subject><subject>Animals</subject><subject>Anterior pituitary</subject><subject>Antibodies</subject><subject>Antigens</subject><subject>Antiserum</subject><subject>Cells</subject><subject>Cellular immunity</subject><subject>Growth Hormone - metabolism</subject><subject>Hormones</subject><subject>Immunoenzyme Techniques</subject><subject>Luteinization</subject><subject>Luteinizing Hormone - biosynthesis</subject><subject>Male</subject><subject>Pituitary Gland, Anterior - cytology</subject><subject>Pituitary Gland, Anterior - metabolism</subject><subject>Prolactin - metabolism</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Renin - metabolism</subject><subject>Sheep</subject><subject>Thyrotropin - metabolism</subject><issn>0027-8424</issn><issn>1091-6490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><recordid>eNp9kc1LHDEYxoO02PXjLAiWOelp1nzNJHPooSxahYWK6DlkMokbmUnWJFOqf72Z7qrtpRASyPN73vdNHgCOEJwjyMj52sk4Z3yO8JxVrNkBMwQbVNa0gZ_ADELMSk4x_QL2YnyEEDYVh7tgt8aMUw5nQF4Pw-j8ysbk1UoPVsm-WPq82xeZrHeFN8WtdtYVeS3HpK2zL9Y9FFc-DN7p8ib4blTTzUL3ffzDy1Tc2DTaJMPzAfhsZB_14fbcB_eXF3eLq3L588f14vuyVBVmqaSE1Fxp2Na4qQmvDK6QUaRRLW6lNLXSssUEaVlB1HLMWtjJumM1J7RT1BiyD75t6q7HdtCd0i4F2Yt1sEOeQnhpxb-Ksyvx4H8JQhuCcPafbv3BP406JjHYqPKTpNN-jIIRzvOPT-D5BlTBxxi0ee-BoJhCEVMognGBsJhCyY6Tv0d757cpZP1sq0_GN_WjgDBj3yf9O2Xy63_JDBxvgMccaPiYDGFakVdNdKzG</recordid><startdate>19811201</startdate><enddate>19811201</enddate><creator>Naruse, Kiyoko</creator><creator>Takii, Yukio</creator><creator>Inagami, Tadashi</creator><general>National Academy of Sciences of the United States of America</general><general>National Acad Sciences</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19811201</creationdate><title>Immunohistochemical Localization of Renin in Luteinizing Hormone-Producing Cells of Rat Pituitary</title><author>Naruse, Kiyoko ; Takii, Yukio ; Inagami, Tadashi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c527t-43368ce0b6296385f251fc39cb2baaf6ceab231ea501b827b0da6d76834dc4ff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Adrenocorticotropic Hormone - metabolism</topic><topic>Animals</topic><topic>Anterior pituitary</topic><topic>Antibodies</topic><topic>Antigens</topic><topic>Antiserum</topic><topic>Cells</topic><topic>Cellular immunity</topic><topic>Growth Hormone - metabolism</topic><topic>Hormones</topic><topic>Immunoenzyme Techniques</topic><topic>Luteinization</topic><topic>Luteinizing Hormone - biosynthesis</topic><topic>Male</topic><topic>Pituitary Gland, Anterior - cytology</topic><topic>Pituitary Gland, Anterior - metabolism</topic><topic>Prolactin - metabolism</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Renin - metabolism</topic><topic>Sheep</topic><topic>Thyrotropin - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Naruse, Kiyoko</creatorcontrib><creatorcontrib>Takii, Yukio</creatorcontrib><creatorcontrib>Inagami, Tadashi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Naruse, Kiyoko</au><au>Takii, Yukio</au><au>Inagami, Tadashi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Immunohistochemical Localization of Renin in Luteinizing Hormone-Producing Cells of Rat Pituitary</atitle><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle><addtitle>Proc Natl Acad Sci U S A</addtitle><date>1981-12-01</date><risdate>1981</risdate><volume>78</volume><issue>12</issue><spage>7579</spage><epage>7583</epage><pages>7579-7583</pages><issn>0027-8424</issn><eissn>1091-6490</eissn><abstract>The location of renin (EC 3.4.99.19) in rat pituitary was determined by the peroxidase-antiperoxidase immunohistochemical technique. By using antisera prepared with purified rat renal renin, an immunoreactive substance was localized within ovoid cells scattered throughout the anterior pituitary. These cells were shown to be luteinizing hormone-producing cells by staining with anti-luteinizing hormone antisera in adjacent sections. By using the double staining method, the renin-containing cells were differentiated from cells containing corticotropin, thyrotropin, growth hormone (somatotropin), and prolactin (mammotropin). These results suggest a possible local role for renin in the anterior pituitary.</abstract><cop>United States</cop><pub>National Academy of Sciences of the United States of America</pub><pmid>6278480</pmid><doi>10.1073/pnas.78.12.7579</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0027-8424
ispartof Proceedings of the National Academy of Sciences - PNAS, 1981-12, Vol.78 (12), p.7579-7583
issn 0027-8424
1091-6490
language eng
recordid cdi_proquest_miscellaneous_73880732
source Open Access: PubMed Central; JSTOR Archival Journals and Primary Sources Collection
subjects Adrenocorticotropic Hormone - metabolism
Animals
Anterior pituitary
Antibodies
Antigens
Antiserum
Cells
Cellular immunity
Growth Hormone - metabolism
Hormones
Immunoenzyme Techniques
Luteinization
Luteinizing Hormone - biosynthesis
Male
Pituitary Gland, Anterior - cytology
Pituitary Gland, Anterior - metabolism
Prolactin - metabolism
Rats
Rats, Inbred Strains
Renin - metabolism
Sheep
Thyrotropin - metabolism
title Immunohistochemical Localization of Renin in Luteinizing Hormone-Producing Cells of Rat Pituitary
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-30T17%3A17%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Immunohistochemical%20Localization%20of%20Renin%20in%20Luteinizing%20Hormone-Producing%20Cells%20of%20Rat%20Pituitary&rft.jtitle=Proceedings%20of%20the%20National%20Academy%20of%20Sciences%20-%20PNAS&rft.au=Naruse,%20Kiyoko&rft.date=1981-12-01&rft.volume=78&rft.issue=12&rft.spage=7579&rft.epage=7583&rft.pages=7579-7583&rft.issn=0027-8424&rft.eissn=1091-6490&rft_id=info:doi/10.1073/pnas.78.12.7579&rft_dat=%3Cjstor_proqu%3E11245%3C/jstor_proqu%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c527t-43368ce0b6296385f251fc39cb2baaf6ceab231ea501b827b0da6d76834dc4ff3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=73880732&rft_id=info:pmid/6278480&rft_jstor_id=11245&rfr_iscdi=true