Inflammatory leiomyosarcoma may be characterized by specific near-haploid chromosome changes

Identical near‐haploid karyotypes with 28, X, +5, +18, +20, +21, +22 were found in two cases of inflammatory leiomyosarcoma, one of which had been reported previously as malignant fibrous histiocytoma. This abnormality may identify these tumours as a separate entity within this group of sarcomas. ©...

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Bibliographic Details
Published in:The Journal of pathology 1998-05, Vol.185 (1), p.112-115
Main Authors: Dal Cin, Paola, Sciot, Raf, Fletcher, Christopher D. M., Samson, Ignace, De Vos, Rita, Mandahl, Nils, Willén, Helena, Larsson, Olle, Van den Berghe, Herman
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
cytogenetics
Dermatology
Diagnosis, Differential
electron microscopy
Haploidy
Histiocytoma, Benign Fibrous - diagnosis
Histiocytoma, Benign Fibrous - genetics
Humans
inflammatory leiomyosarcoma
Karyotyping
Leiomyosarcoma - diagnosis
Leiomyosarcoma - genetics
Leiomyosarcoma - ultrastructure
Male
malignant fibrous histiocytoma
Medical sciences
near-haploid karyotype
Soft Tissue Neoplasms - diagnosis
Soft Tissue Neoplasms - genetics
Soft Tissue Neoplasms - ultrastructure
Tumors of the skin and soft tissue. Premalignant lesions
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Summary:Identical near‐haploid karyotypes with 28, X, +5, +18, +20, +21, +22 were found in two cases of inflammatory leiomyosarcoma, one of which had been reported previously as malignant fibrous histiocytoma. This abnormality may identify these tumours as a separate entity within this group of sarcomas. © 1998 John Wiley & Sons, Ltd.
ISSN:0022-3417
1096-9896
DOI:10.1002/(SICI)1096-9896(199805)185:1<112::AID-PATH54>3.0.CO;2-U