A prospective randomized trial of triage angiography in acute coronary syndromes ineligible for thrombolytic therapy results of the medicine versus angiography in thrombolytic exclusion (mate) trial

• Published in: Journal of the American College of Cardiology 1998-09, Vol.32 (3), p.596-605
• Main Authors: MCCULLOUGH, P. A, O'NEILL, W. W, GRAHAM, M, STOMEL, R. J, ROGERS, F, DAVID, S, FARHAT, A, KAZLAUSKAITE, R, AL-ZAGOUM, M, GRINES, C. L
• Format: Article
• Language: English
• Subjects: Adult; Aged; Biological and medical sciences; Cardiovascular system; Cause of Death; Coronary Angiography; Coronary Disease - diagnostic imaging; Coronary Disease - mortality; Coronary Disease - therapy; Female; Hospital Mortality; Humans; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Middle Aged; Myocardial Infarction - diagnostic imaging; Myocardial Infarction - mortality; Myocardial Infarction - therapy; Myocardial Revascularization; Prognosis; Prospective Studies; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Sensitivity and Specificity; Thrombolytic Therapy; Treatment Outcome; Triage
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/S0735-1097(98)00284-8

The purpose of this study was to determine if early triage angiography with revascularization, if indicated, favorably affects clinical outcomes in patients with suspected acute myocardial infarction who are ineligible for thrombolysis. The majority of patients with acute myocardial infarction and other acute coronary syndromes are considered ineligible for thrombolysis and therefore are not afforded the opportunity for early reperfusion. This multicenter, prospective, randomized trial evaluated in a controlled fashion the outcomes following triage angiography in acute coronary syndromes ineligible for thrombolytic therapy. Eligible patients (n=201) with