Pattern of left ventricular filling in hypertrophic cardiomyopathy : Assessment by Doppler echocardiography and radionuclide angiography

The left ventricle in hypertrophic cardiomyopathy is anatomically and functionally non-uniform. This study was undertaken to verify whether a heterogeneity in the pattern of diastolic filling can be detected along the left ventricular inflow tract in hypertrophic cardiomyopathy. Early (E) and late (...

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Bibliographic Details
Published in:European heart journal 1998-08, Vol.19 (8), p.1261-1267
Main Authors: LOSI, M. A, BETOCCHI, S, MANGANELLI, F, BRIGUORI, C, CIAMPI, Q, PERRONE-FILARDI, P, PACE, L, SALVATORE, M, CHIARIELLO, M
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Cardiology. Vascular system
Cardiomyopathy, Hypertrophic - diagnostic imaging
Cardiomyopathy, Hypertrophic - physiopathology
Child
Diastole
Echocardiography, Doppler
Female
Heart
Humans
Male
Medical sciences
Middle Aged
Multivariate Analysis
Myocarditis. Cardiomyopathies
Radionuclide Angiography
Ventricular Dysfunction, Left
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Summary:The left ventricle in hypertrophic cardiomyopathy is anatomically and functionally non-uniform. This study was undertaken to verify whether a heterogeneity in the pattern of diastolic filling can be detected along the left ventricular inflow tract in hypertrophic cardiomyopathy. Early (E) and late (A) diastolic velocities were recorded by Doppler echocardiography at mitral and at mid-ventricular level in 16 normal volunteers and 30 patients with hypertrophic cardiomyopathy. Patients with hypertrophic cardiomyopathy also underwent radionuclide angiography to assess left ventricular function. E wave decreased significantly in normal volunteers (80 +/- 15 to 60 +/- 14 cm x s(-1); P
ISSN:0195-668X
1522-9645
DOI:10.1053/euhj.1998.0978