Prolonged exercise increases peripheral plasma ACTH, CRH, and AVP in male athletes

• Published in: Journal of applied physiology (1985) 1998-09, Vol.85 (3), p.835-841
• Main Authors: Inder, W. J, Hellemans, J, Swanney, M. P, Prickett, T. C. R, Donald, R. A
• Format: Article
• Language: English
• Subjects: Adrenocorticotropic Hormone - blood; Adult; Anatomy & physiology; Arginine Vasopressin - blood; Biological and medical sciences; Blood Glucose - metabolism; Corticotropin-Releasing Hormone - blood; Enzyme-Linked Immunosorbent Assay; Exercise; Exercise - physiology; Fundamental and applied biological sciences. Psychology; Hormones; Humans; Male; Men; Osmolar Concentration; Oxygen Consumption - physiology; Physical Fitness; Plasma; Respiratory Mechanics - physiology; Sports; Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports
• ISSN: 8750-7587; 1522-1601
• DOI: 10.1152/jappl.1998.85.3.835

Departments of 1  Endocrinology and 2  Respiratory Medicine, Christchurch Hospital, and 3  Sportsmed, Christchurch, New Zealand We wished to determine whether the increased ACTH during prolonged exercise was associated with changes in peripheral corticotropin-releasing hormone (CRH) and/or arginine vasopressin (AVP). Six male triathletes were studied during exercise: 1 h at 70% maximal oxygen consumption, followed by progressively increasing work rates until exhaustion. Data obtained during the exercise session were compared with a nonexercise control session. Venous blood was sampled over a 2-h period for cortisol, ACTH, CRH, AVP, renin, glucose, and plasma osmolality. There were significant increases by ANOVA on log-transformed data in plasma cortisol ( P  = 0.002), ACTH ( P