Differentiation of neurons in the locus ceruleus after allotransplantation into previously denervated white rat hippocampus

The aims of the present work were to study the morphological characteristics of allotransplants of embryonic locus ceruleus (LC) in the hippocampus of animals with previously lesioned brain noradrenergic systems and to study the potential compensatory effects of LC allotransplants on orientational-i...

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Bibliographic Details
Published in:Neuroscience and behavioral physiology 1998-07, Vol.28 (4), p.349-353
Main Authors: Svanidze, I K, Tsaishvili, Ts S, Kokaya, Z G, Godziashvili, S B, Kokaya, M G
Format: Article
Language:English
Subjects:
Animals
Brain Tissue Transplantation
Cell Differentiation - physiology
Denervation
Exploratory Behavior - physiology
Fetal Tissue Transplantation
Hippocampus - cytology
Hippocampus - physiology
Hippocampus - surgery
Immunohistochemistry
Locus Coeruleus - cytology
Locus Coeruleus - embryology
Locus Coeruleus - transplantation
Neurons - physiology
Norepinephrine - physiology
Orientation - physiology
Rats
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Summary:The aims of the present work were to study the morphological characteristics of allotransplants of embryonic locus ceruleus (LC) in the hippocampus of animals with previously lesioned brain noradrenergic systems and to study the potential compensatory effects of LC allotransplants on orientational-investigative activity in rats after inactivation of the brain's noradrenergic system.
ISSN:0097-0549
1573-899X
DOI:10.1007/BF02464786