Cardiac surgery with extracorporeal circulation in 23 infants weighing 2500 g or less: short and intermediate term outcome

• Published in: European journal of cardio-thoracic surgery 1998-08, Vol.14 (2), p.165-172
• Main Authors: Beyens, T., Biarent, D., Bouton, J.M., Demanet, H., Viart, P., Dessy, H., Devillé, A., Lamote, J., Deuvaert, F.E.
• Format: Article
• Language: English
• Subjects: Biological and medical sciences; Body Weight; Cardiac surgery; Cardiac Surgical Procedures - mortality; Extracorporeal Circulation; Female; Follow-Up Studies; Heart Defects, Congenital - mortality; Heart Defects, Congenital - surgery; Humans; Infant, Low Birth Weight; Infant, Newborn; Low birth-weight; Male; Medical sciences; Morbidity; Neonates; Postoperative Complications - epidemiology; Retrospective Studies; Risk Factors; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Time Factors; Treatment Outcome
• ISSN: 1010-7940; 1873-734X
• DOI: 10.1016/S1010-7940(98)00158-4

Objective and methods: From September 1990 to February 1997, 23 consecutive critically ill infants (12 males, 11 females) weighing 2500 g or less underwent cardiac surgery necessitating extracorporeal circulation (ECC). A retrospective study was carried out to evaluate short- and intermediate-term outcome. Mean weight at operation was 2265 g (range 1750–2500 g). Mean age at operation was 24 days. The indications for surgery were transposition of the great arteries (TGA; 7), ventricular septal defect (VSD; 4), aortic stenosis (AS; 3), univentricular heart (UVH; 2), tetralogy of Fallot (TOF; 2), interrupted aortic arch (IAA; 2), atrial septal defect (ASD; 1), atrioventicular septal defect (AVSD; 1) and total abnormal pulmonary venous return (TAPVR; 1). All patients were in NYHA class IV; 17 patients (74%) were intubated pre-operatively. Results: The mean aortic cross-clamping time was 40 min. Twelve patients required deep hypothermia (