Proton magnetic resonance spectroscopy of fetal lamb brain during hypoxia

Proton magnetic resonance spectroscopy of fetal lamb brain was performed simultaneously with repeated measurements of fetal arterial oxygen saturation during decrease of oxygen supply. Magnetic resonance spectra displayed the same metabolite peaks as detected in the human fetal brain. Cerebral lacta...

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Bibliographic Details
Published in:American journal of obstetrics and gynecology 1998-09, Vol.179 (3), p.756-757
Main Authors: van Cappellen van Walsum, Anne-Marie, Heerschap, Arend, Nijhuis, Jan G., Oeseburg, Berend, Jongsma, Henk W.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Brain - embryology
Brain - metabolism
Diseases of mother, fetus and pregnancy
Fetal Blood - metabolism
Fetal Hypoxia - blood
Fetal Hypoxia - diagnosis
Fetal Hypoxia - metabolism
Fetal lamb brain
Fetus - metabolism
Gynecology. Andrology. Obstetrics
hypoxia
lactate
Lactic Acid - blood
Lactic Acid - metabolism
Magnetic Resonance Spectroscopy
Medical sciences
Oxygen - blood
Oxygen - metabolism
Pregnancy. Fetus. Placenta
proton magnetic resonance spectroscopy
Sheep - embryology
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Summary:Proton magnetic resonance spectroscopy of fetal lamb brain was performed simultaneously with repeated measurements of fetal arterial oxygen saturation during decrease of oxygen supply. Magnetic resonance spectra displayed the same metabolite peaks as detected in the human fetal brain. Cerebral lactate signals could be detected during fetal hypoxia. (Am J Obstet Gynecol 1998;179:756-7.)
ISSN:0002-9378
1097-6868
DOI:10.1016/S0002-9378(98)70077-8