Efficacy of one dose fluoroquinolone before prostate biopsy

Objectives. To demonstrate the efficacy of a simple preparation for prostate biopsy (PBX) and to determine its potential cost savings. Methods. One hundred fifty consecutive PBXs were performed using a Fleet enema and a single oral dose (300 mg) of ofloxacin as the pre-PBX preparation. Results. Of t...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 1998-10, Vol.52 (4), p.641-643
Main Authors: Shandera, Kevin C., Thibault, Gregory P., Deshon, George E.
Format: Article
Language:English
Subjects:
Anti-Infective Agents - administration & dosage
Antibacterial agents
Antibiotic Prophylaxis - economics
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Biopsy, Needle
Costs and Cost Analysis
Follow-Up Studies
Humans
Male
Medical sciences
Ofloxacin - administration & dosage
Pharmacology. Drug treatments
Prospective Studies
Prostatic Neoplasms - pathology
Urinary Tract Infections - prevention & control
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Summary:Objectives. To demonstrate the efficacy of a simple preparation for prostate biopsy (PBX) and to determine its potential cost savings. Methods. One hundred fifty consecutive PBXs were performed using a Fleet enema and a single oral dose (300 mg) of ofloxacin as the pre-PBX preparation. Results. Of the 150 PBXs we performed, only 1 (0.67%) patient developed a urinary tract infection. Conclusions. A simple and inexpensive pre-PBX preparation proved to be successful in preventing infectious complications and is presented as a potential model for inclusion in clinical pathways for diagnosing adenocarcinoma of the prostate.
ISSN:0090-4295
1527-9995
DOI:10.1016/S0090-4295(98)00311-2