Homogeneously staining regions in direct preparations from human neuroblastomas

Previous descriptions of homogeneously staining regions in human neuroblastomas have been in karyotypes obtained from established cell lines. We now report homogeneously staining regions in direct preparations from two human neuroblastomas. In one of the cases, the homogeneously staining region iden...

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Bibliographic Details
Published in:Cancer research (Chicago, Ill.) Ill.), 1982-05, Vol.42 (5), p.1838-1842
Main Authors: Balaban, G, Gilbert, F
Format: Article
Language:English
Subjects:
Bone Marrow - ultrastructure
Chromosomes - ultrastructure
Female
Humans
Infant
Karyotyping
Male
Metaphase
Neoplasm Metastasis
Neuroblastoma - genetics
Neuroblastoma - ultrastructure
Staining and Labeling
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Summary:Previous descriptions of homogeneously staining regions in human neuroblastomas have been in karyotypes obtained from established cell lines. We now report homogeneously staining regions in direct preparations from two human neuroblastomas. In one of the cases, the homogeneously staining region identified in the primary tumor was also found in metastases to bone marrow and pleural fluid. The homogeneously staining region is, therefore, not an artifact of growth in vitro.
ISSN:0008-5472