IDENTIFICATION OF ANTIBIOTICS OF ITURIN GROUP IN VARIOUS STRAINS OF BACILLUS SUBTILIS

Thirty eight strains of B. subtilis were tested for the presence of antifungal antibiotics of the iturin group. The characterization of these antibiotics was made on the basis of: antifungal activity against P. chrysogenum, isolation and purification of the active substance, quantitative analysis of...

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Bibliographic Details
Published in:Journal of antibiotics 1978, Vol.31(4), pp.284-288
Main Authors: BESSON, FRANCOISE, PEYPOUX, FRANCOISE, MICHEL, GEORGES, DELCAMBE, LUCIEN
Format: Article
Language:English
Subjects:
Antifungal Agents - analysis
Antifungal Agents - biosynthesis
Antifungal Agents - pharmacology
Bacillus subtilis - metabolism
Hydrolysis
Penicillium chrysogenum - drug effects
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Summary:Thirty eight strains of B. subtilis were tested for the presence of antifungal antibiotics of the iturin group. The characterization of these antibiotics was made on the basis of: antifungal activity against P. chrysogenum, isolation and purification of the active substance, quantitative analysis of α-aminoacids and identification of the liposoluble dipeptide obtained by partial hydrolysis. The only antibiotics of the iturin group found were: iturin A, mycosubtilin and bacillomycin L.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.31.284