A method for classification of 5′ termini of retroviruses

A new method for the classification of retroviruses is presented. The scheme is based on the length and sequence of a DNA transcript of the 5′ end of the genome. The method can be used to detect similarities between distantly related viruses as well as to discriminate between very closely related vi...

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Bibliographic Details
Published in:Nature (London) 1978-06, Vol.273 (5661), p.358-364
Main Authors: Haseltine, William A, Kleid, Dennis G
Format: Article
Language:English
Subjects:
Alpharetrovirus - classification
Animals
Base Sequence
DNA, Viral - metabolism
Humanities and Social Sciences
Hylobates - microbiology
Leukemia Virus, Murine - classification
Molecular Weight
multidisciplinary
Papio - microbiology
Pyrimidines
Retroviridae - classification
RNA, Viral - metabolism
RNA-Directed DNA Polymerase - metabolism
Sarcoma Virus, Woolly Monkey - classification
Science
Science (multidisciplinary)
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Summary:A new method for the classification of retroviruses is presented. The scheme is based on the length and sequence of a DNA transcript of the 5′ end of the genome. The method can be used to detect similarities between distantly related viruses as well as to discriminate between very closely related viruses. The method is applied to viruses isolated from mice, baboons, gibbons, a woolly monkey and chickens.
ISSN:0028-0836
1476-4687
DOI:10.1038/273358a0