nature of the collagen in hepatic fibrosis in advanced murine schistosomiasis

Schistosoma mansoni-infected CF1 mice, collagen content of livers had increased 18-fold by 8 weeks postinfection, may provide an important model for study of possible reversibility of fibrotic hepatic lesions

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Bibliographic Details
Published in:Hepatology (Baltimore, Md.) Md.), 1982-05, Vol.2 (3), p.366-371
Main Authors: Wu, C.H, Giambrone, M.A, Howard, D.J, Rojkind, M, Wu, G.Y
Format: Article
Language:English
Subjects:
Amino Acids - analysis
Animals
Chemical Phenomena
Chemistry
Chromatography - methods
Collagen - metabolism
Female
liver
Liver Diseases, Parasitic - metabolism
Liver Diseases, Parasitic - pathology
Mice
Pathology, Trematoda
Proteins, Host
Schistosoma mansoni
Schistosomiasis - metabolism
Technique, Experimental hosts
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Description
Summary:Schistosoma mansoni-infected CF1 mice, collagen content of livers had increased 18-fold by 8 weeks postinfection, may provide an important model for study of possible reversibility of fibrotic hepatic lesions
ISSN:0270-9139
1527-3350
DOI:10.1002/hep.1840020313