Urinary excretion of calcium following an oral calcium loading test in healthy children

Extract: The ratio of urinary calcium (UCa)/urinary creatinine (UCr) concentrations (mg/mg) during calcium loading has been used to diagnose hypercalciuric states in adults. The UCa/UCr ratios have been examined before and after an oral dose of calcium in 48 healthy children following 5 days of abst...

Full description

Saved in:
Bibliographic Details
Published in:Pediatrics (Evanston) 1982-05, Vol.69 (5), p.594-597
Main Authors: Stapleton, F. Bruder, Noe, H. Norman, Jerkins, Gerald, Roy, Shane III
Format: Article
Language:English
Subjects:
absorption
Adolescent
calcium
Calcium - metabolism
Calcium - urine
Child
Child, Preschool
children
Creatinine - urine
Diet
excretion
Female
Humans
Male
nutrient intake
nutrient retention
Reference Values
Sodium - urine
urine analysis
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Extract: The ratio of urinary calcium (UCa)/urinary creatinine (UCr) concentrations (mg/mg) during calcium loading has been used to diagnose hypercalciuric states in adults. The UCa/UCr ratios have been examined before and after an oral dose of calcium in 48 healthy children following 5 days of abstinence from dietary milk products. No differences in UCa/UCr ratios were observed between sexes, races, or age groups. The mean UCa/UCr ratio before the calcium dose was 0.09; it increased to 0.12 in urine samples collected for 4 hours after the calcium load. A direct relationship between the UCa/UCr ratio and the urinary sodium UCr ratio was observed. In 6 children, calcium loading studies were repeated without prior restriction of dietary calcium. Dietary calcium intake before the calcium loading had little effect upon the UCa/UCr ratio before the calcium dose in these 6 children (0.068 vs 0.08); however, UCa/UCr values after the calcium load were significantly lower (0.08 vs 0.15) when no dietary calcium restriction preceded the calcium-loading study. These data may allow characterization of renal hypercalciuria and gastrointestinal hyperabsorption of calcium in children with urolithiasis. (author)
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.69.5.594