Suspected Acute Cholecystitis Comparison of Hepatobiliary Scintigraphy Versus Ultrasonography

One hundred ninety-fine patients with suspected acute cholecystitis (AC) underwent both hepatobiliary scintigraphy (HBS) and static gray-scale ultrasonography (US) to assess the relative value of each imaging modality in this clinical setting. HBS was performed after the intravenous injection of 5 m...

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Bibliographic Details
Published in:Clinical nuclear medicine 1982-08, Vol.7 (8), p.364-367
Main Authors: FREITAS, J E, MIRKES, S H, FINK-BENNETT, D M, BREE, R L
Format: Article
Language:English
Subjects:
Acute Disease
Biliary Tract - diagnostic imaging
Cholecystitis - diagnosis
Cholecystitis - diagnostic imaging
Humans
Imino Acids
Liver - diagnostic imaging
Organotechnetium Compounds
Prospective Studies
Radionuclide Imaging
Technetium
Time Factors
Ultrasonography
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Summary:One hundred ninety-fine patients with suspected acute cholecystitis (AC) underwent both hepatobiliary scintigraphy (HBS) and static gray-scale ultrasonography (US) to assess the relative value of each imaging modality in this clinical setting. HBS was performed after the intravenous injection of 5 mCi Tc-99m iprofenin. Abnormal HBS indicative of AC visualized the common bile duct, but not the gallbladder, within 1 to 4 hours after tracer administration. Abnormal US indicative of AC demonstrated cholelithiasis and/or gallbladder wall edema. In this series, HBS surpassed US in sensitivity (98.3% versus 81.4%), specificity (90.2% versus 60.2%), predictive value of an abnormal test (91.4% versus 51.6%), and predictive value of a normal test (100% versus 92%), HBS should be the procedure of choice for the rapid detection of AC.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-198208000-00004