Oral Lecithin and Linoleic Acid in Friedreich’s Ataxia: I. Design of the Study, Material and Methods

A clinical and biochemical evaluation of twenty-two patients with Friedreich’s Ataxia and ten normal controls was undertaken in 1980 to assess the effect of lecithin and linoleic acid supplements on the course of the disease. The trial consisted of two consecutive six months periods on either supple...

Full description

Saved in:
Bibliographic Details
Published in:Canadian journal of neurological sciences 1982-05, Vol.9 (2), p.151-154
Main Authors: Melancon, S.B., Dallaire, L., Potier, M., Vanasse, M., Marois, P., Geoffroy, G., Barbeau, A.
Format: Article
Language:English
Subjects:
Administration, Oral
Adolescent
Adult
Child
Clinical Trials as Topic
Double-Blind Method
Female
Friedreich Ataxia - drug therapy
Humans
Linoleic Acid
Linoleic Acids - therapeutic use
Locomotion - drug effects
Male
Motor Skills - drug effects
Muscle Contraction - drug effects
Phosphatidylcholines - therapeutic use
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A clinical and biochemical evaluation of twenty-two patients with Friedreich’s Ataxia and ten normal controls was undertaken in 1980 to assess the effect of lecithin and linoleic acid supplements on the course of the disease. The trial consisted of two consecutive six months periods on either supplements in a double-blind crossover fashion. Clinical appraisal was performed with regards to the following parameters: joints mobility, muscle strength, equilibrium, coordination, motor accuracy, speech and numerous day to day activities. Blood samples were obtained at the beginning and in the course of the trial for enzymatic determinations. This paper describes the methodology of the study.
ISSN:0317-1671
2057-0155
DOI:10.1017/S0317167100043869