Transbronchial lung biopsy in the diagnosis of lymphangitic carcinomatosis

The clinical diagnosis of lymphangitic carcinomatosis of the lung has generally been confirmed by open lung or transthoracic needle biopsy, precedures with significant morbidity and mortality, particularly in patients with respiratory insufficiency. We present six cases of lymphangitic carcinomatosi...

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Bibliographic Details
Published in:Cancer 1978-10, Vol.42 (4), p.1995-1998
Main Authors: Aranda, Conrado, Sidhu, G., Sasso, Louis A., Adams, Francis V.
Format: Article
Language:English
Subjects:
Adenocarcinoma - diagnosis
Adenocarcinoma - ultrastructure
Biopsy - methods
Carcinoma, Small Cell - diagnosis
Carcinoma, Squamous Cell - diagnosis
Humans
Lung Neoplasms - diagnosis
Lung Neoplasms - ultrastructure
Lymphangitis - diagnosis
Male
Microscopy, Electron
Middle Aged
Neoplasm Metastasis - diagnosis
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Summary:The clinical diagnosis of lymphangitic carcinomatosis of the lung has generally been confirmed by open lung or transthoracic needle biopsy, precedures with significant morbidity and mortality, particularly in patients with respiratory insufficiency. We present six cases of lymphangitic carcinomatosis diagnosed by transbronchial biopsy. Autopsy confirmation was obtained in 4 patients and ultrastructural confirmation of intralymphatic location of tumor in one. The diffuse bronchial and peribronchial lymphatic involvement demonstrated here suggests that this relatively noninvasive technique should be the procedure of choice in the diagnosis of lymphangitic carcinomatosis of the lung. Cancer 42:1995‐1998, 1978.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(197810)42:4<1995::AID-CNCR2820420446>3.0.CO;2-C