Serum haptoglobulin changes in patients with severe isolated head injury

From a series of 74 patients with severe head injuries and massive brain lesions, we measured the changes in haptoglobulin in 33 cases. On average, the globulin was, after a short drop in the first two days, increased about three times towards the seventh day, and was still above normal after ten da...

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Bibliographic Details
Published in:Acta neurochirurgica 1978-01, Vol.42 (3-4), p.229-234
Main Authors: Auer, L, Petek, W
Format: Article
Language:English
Subjects:
Adult
Alpha-Globulins - analysis
alpha-Macroglobulins - analysis
Brain Injuries - blood
Haptoglobins - analysis
Humans
Male
Middle Aged
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Summary:From a series of 74 patients with severe head injuries and massive brain lesions, we measured the changes in haptoglobulin in 33 cases. On average, the globulin was, after a short drop in the first two days, increased about three times towards the seventh day, and was still above normal after ten days. Seen together with the total alpha-2-globulin increase after head injury this rise seems mainly to be caused by the haptoglobulin changes. Haptoglobulin was found to be a good indicator of the extent of brain tissue damage. It cannot on its own be used for prediction of survival chances.
ISSN:0001-6268
0942-0940
DOI:10.1007/BF01405338