Detection of human carcinogens

Rodent cancer bioassays are not the most efficient method of detecting possible human carcinogens. An alternative method is to conduct short-term tests for effects associated with rodent carcinogenicity and to conduct limited cancer tests when more precise knowledge about carcinogenicity of a chemic...

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Bibliographic Details
Published in:Nature (London) 1991-07, Vol.352 (6332), p.185-186
Main Authors: Ashby, J, Morrod, R. S
Format: Article
Language:English
Subjects:
Animals
Bioassays
Biological and medical sciences
Cancer
Carcinogenesis, carcinogens and anticarcinogens
Carcinogenicity
Carcinogens
Carcinogens - toxicity
Chemical agents
Chemicals
Humans
Medical sciences
Neoplasms - chemically induced
Neoplasms, Experimental - chemically induced
Rodentia
Rodents
Toxicology - methods
Tumors
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Summary:Rodent cancer bioassays are not the most efficient method of detecting possible human carcinogens. An alternative method is to conduct short-term tests for effects associated with rodent carcinogenicity and to conduct limited cancer tests when more precise knowledge about carcinogenicity of a chemical is required.
ISSN:0028-0836
1476-4687
DOI:10.1038/352185a0