Dynamic interactions of cyclic AMP transients and spontaneous Ca2+ spikes

The authors report observations of spontaneous increases in concentration of cyclic AMP (cAMP) in embryonic spinal neurons, and their dynamic interactions with Ca2+ oscillations. A mathematical model of Ca2+-cAMP is discussed.

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Bibliographic Details
Published in:Nature (London) 2002-07, Vol.418 (6893), p.93-96
Main Authors: Gorbunova, Yuliya V, Spitzer, Nicholas C
Format: Article
Language:English
Subjects:
Calcium
Kinetics
Mathematical models
Nervous system
Neurons
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Description
Summary:The authors report observations of spontaneous increases in concentration of cyclic AMP (cAMP) in embryonic spinal neurons, and their dynamic interactions with Ca2+ oscillations. A mathematical model of Ca2+-cAMP is discussed.
ISSN:0028-0836
1476-4687
DOI:10.1038/nature00835