Microbial production of fructosyltransferases for synthesis of pre-biotics

Fructooligosaccharides (FOS) are prebiotic substances found in several vegetable or natural foods. The main commercial production of FOS comes from enzymatic transformation of sucrose by the microbial enzyme fructosyltransferase. The development of more efficient enzymes, with high activity and stab...

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Bibliographic Details
Published in:Biotechnology letters 2008-11, Vol.30 (11), p.1867-1877
Main Authors: Maiorano, Alfredo Eduardo, Piccoli, Rosane Moniz, da Silva, Elda Sabino, de Andrade Rodrigues, Maria Filomena
Format: Article
Language:English
Subjects:
Applied Microbiology
Aspergillus - enzymology
Aspergillus - growth & development
Aspergillus - metabolism
Biochemistry
Biological and medical sciences
Biomedical and Life Sciences
Biotechnology
Diet
Enzymes
Fermentation
Fundamental and applied biological sciences. Psychology
Hexosyltransferases - metabolism
Industrial Microbiology - methods
Life Sciences
Microbiology
Microorganisms
Natural & organic foods
Nutrition
Oligosaccharides - chemistry
Oligosaccharides - metabolism
Review
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Summary:Fructooligosaccharides (FOS) are prebiotic substances found in several vegetable or natural foods. The main commercial production of FOS comes from enzymatic transformation of sucrose by the microbial enzyme fructosyltransferase. The development of more efficient enzymes, with high activity and stability, is required and this has attracted the interest of biotechnologists and microbiologists with production by several microorganisms being studied. This article reviews and discusses FOS chemical structure, enzyme characteristics, the nomenclature, producer microorganisms and enzyme production both in solid state fermentation and submerged cultivation.
ISSN:0141-5492
1573-6776
DOI:10.1007/s10529-008-9793-3