Intramembrane Proteases: Mixing Oil and Water

There are four classes of proteases and peptidases classified according to which amino acid residues in the enzyme catalyze the breaking of an amide bond in the substrate. Research by Weihofen and colleagues on a hydrolase is discussed.

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Published in:Science (American Association for the Advancement of Science) 2002-06, Vol.296 (5576), p.2156-2157
Main Authors: Wolfe, Michael S., Selkoe, Dennis J.
Format: Article
Language:English
Subjects:
Active sites
Amino acids
Atoms
Biochemistry
Catalysts
Enzymes
Lasers
Membrane proteins
P branes
Peptides
Perspectives
Presenilins
Proteases
Signal peptides
String theory
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container_title Science (American Association for the Advancement of Science)
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creator Wolfe, Michael S.
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description There are four classes of proteases and peptidases classified according to which amino acid residues in the enzyme catalyze the breaking of an amide bond in the substrate. Research by Weihofen and colleagues on a hydrolase is discussed.
doi_str_mv 10.1126/science.1073844
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subjects Active sites
Amino acids
Atoms
Biochemistry
Catalysts
Enzymes
Lasers
Membrane proteins
P branes
Peptides
Perspectives
Presenilins
Proteases
Signal peptides
String theory
title Intramembrane Proteases: Mixing Oil and Water
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