Anterior Cingulate: Single Neuronal Signals Related to Degree of Reward Expectancy

As monkeys perform schedules containing several trials with a visual cue indicating reward proximity, their error rates decrease as the number of remaining trials decreases, suggesting that their motivation and/or reward expectancy increases as the reward approaches. About one-third of single neuron...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2002-05, Vol.296 (5573), p.1709-1711
Main Authors: Shidara, Munetaka, Richmond, Barry J.
Format: Article
Language:English
Subjects:
Action Potentials
Analysis of Variance
Anatomical correlates of behavior
Animal behavior
Animal memory
Animals
Anxiety Disorders
Behavior, Animal
Behavioral neuroscience
Behavioral psychophysiology
Biological and medical sciences
Brain
Brain Mapping
Cues
Drug Abuse
Error rates
Expectation
Experimentation
Feedback (Response)
Fundamental and applied biological sciences. Psychology
Gyrus Cinguli - physiology
Macaca mulatta
Monkeys & apes
Motivation
Neural Pathways
Neurology
Neurons
Neurons - physiology
Neuroscience
Obsessive-Compulsive Disorder - physiopathology
Physiological aspects
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Random Allocation
Research Methodology
Reward
Statistical Analysis
Stimuli
Substance-Related Disorders - physiopathology
Visual Stimuli
Yokes
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Description
Summary:As monkeys perform schedules containing several trials with a visual cue indicating reward proximity, their error rates decrease as the number of remaining trials decreases, suggesting that their motivation and/or reward expectancy increases as the reward approaches. About one-third of single neurons recorded in the anterior cingulate cortex of monkeys during these reward schedules had responses that progressively changed strength with reward expectancy, an effect that disappeared when the cue was random. Alterations of this progression could be the basis for the changes from normal that are reported in anterior cingulate population activity for obsessive-compulsive disorder and drug abuse, conditions characterized by disturbances in reward expectancy.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.1069504