PCR in a Rayleigh-Bénard Convection Cell

The inherent structure of Rayleigh-Bernard convection is ideally suited for performing thermally activated chemical reactions that require temperature cycling. Krishnan et al developed a device that uses Rayleigh-Benard convection to perform polymerase chain reaction (PCR) amplification of DNA insid...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2002-10, Vol.298 (5594), p.793-793
Main Authors: Krishnan, Madhavi, Ugaz, Victor M., Burns, Mark A.
Format: Article
Language:English
Subjects:
Actins - genetics
Biochemistry
Biological and medical sciences
Biotechnology
Brevia
Chemical reactions
Climate
Convection
Convective flow
Deoxyribonucleic acid
DNA
Flow distribution
Fundamental and applied biological sciences. Psychology
Genetic engineering
Genetic technics
Humans
In vitro gene amplification. Pcr technique
Methods. Procedures. Technologies
Motion
Polymerase chain reaction
Polymerase Chain Reaction - instrumentation
Polymerase Chain Reaction - methods
Rayleigh Benard convection
Surface temperature
Temperature
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Summary:The inherent structure of Rayleigh-Bernard convection is ideally suited for performing thermally activated chemical reactions that require temperature cycling. Krishnan et al developed a device that uses Rayleigh-Benard convection to perform polymerase chain reaction (PCR) amplification of DNA inside a 35-mul cylindrical cavity.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.298.5594.793