Violacein: properties and biological activities

The violet pigment violacein is an indole derivative, isolated mainly from bacteria of the genus Chromobacterium, which exhibits important antitumoural, antimicrobial and antiparasitary properties. Furthermore, the formulation of violacein in different polymeric carriers developed so far offers alte...

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Bibliographic Details
Published in:Biotechnology and applied biochemistry 2007-11, Vol.48 (3), p.127-133
Main Authors: Durán, Nelson, Justo, Giselle Z., Ferreira, Carmen V., Melo, Patrícia S., Cordi, Livia, Martins, Dorival
Format: Article
Language:English
Subjects:
Anti-Infective Agents - adverse effects
Anti-Infective Agents - chemistry
Anti-Infective Agents - pharmacology
antimicrobial
Antineoplastic Agents - adverse effects
Antineoplastic Agents - chemistry
Antineoplastic Agents - pharmacology
antiparasitary
antitumoral
Biological and medical sciences
Biotechnology
Chromobacterium
Chromobacterium - chemistry
Fundamental and applied biological sciences. Psychology
Humans
indole derivative
Indoles - adverse effects
Indoles - chemistry
Indoles - pharmacology
violacein
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Summary:The violet pigment violacein is an indole derivative, isolated mainly from bacteria of the genus Chromobacterium, which exhibits important antitumoural, antimicrobial and antiparasitary properties. Furthermore, the formulation of violacein in different polymeric carriers developed so far offers alternative approaches to overcoming physiological barriers and undesirable physicochemical properties in vivo, thus improving its efficacy.
ISSN:0885-4513
1470-8744
DOI:10.1042/BA20070115