Dysfunction in the Neural Circuitry of Emotion Regulation: A Possible Prelude to Violence

Emotion is normally regulated in the human brain by a complex circuit consisting of the orbital frontal cortex, amygdala, anterior cingulate cortex, and several other interconnected regions. There are both genetic and environmental contributions to the structure and function of this circuitry. We po...

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Published in:Science (American Association for the Advancement of Science) 2000-07, Vol.289 (5479), p.591-594
Main Authors: Davidson, Richard J., Putnam, Katherine M., Larson, Christine L.
Format: Article
Language:English
Subjects:
Affect
Affective Behavior
Aggression
Aggressiveness
Aggressiveness (Psychology)
Amygdala
Amygdala (Brain)
Amygdala - physiology
Analysis
Anger
Animals
At Risk Persons
Behavioral neuroscience
Brain
Brain - physiology
Brain chemistry
Brain damage
Cues
Emotion
Emotional expression
Emotional Response
Emotions
Fear
Gene expression regulation
Human aggression
Humans
Impulse
Impulsive Behavior
Impulsivity
Individual Differences
Nervous system
Neural conduction
Neural Pathways
Prefrontal cortex
Prefrontal Cortex - physiology
Psychological Patterns
Psychological Studies
Reviews
Serotonin - physiology
Stimuli
Violence
Violence research
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description Emotion is normally regulated in the human brain by a complex circuit consisting of the orbital frontal cortex, amygdala, anterior cingulate cortex, and several other interconnected regions. There are both genetic and environmental contributions to the structure and function of this circuitry. We posit that impulsive aggression and violence arise as a consequence of faulty emotion regulation. Indeed, the prefrontal cortex receives a major serotonergic projection, which is dysfunctional in individuals who show impulsive violence. Individuals vulnerable to faulty regulation of negative emotion are at risk for violence and aggression. Research on the neural circuitry of emotion regulation suggests new avenues of intervention for such at-risk populations.
doi_str_mv 10.1126/science.289.5479.591
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subjects Affect
Affective Behavior
Aggression
Aggressiveness
Aggressiveness (Psychology)
Amygdala
Amygdala (Brain)
Amygdala - physiology
Analysis
Anger
Animals
At Risk Persons
Behavioral neuroscience
Brain
Brain - physiology
Brain chemistry
Brain damage
Cues
Emotion
Emotional expression
Emotional Response
Emotions
Fear
Gene expression regulation
Human aggression
Humans
Impulse
Impulsive Behavior
Impulsivity
Individual Differences
Nervous system
Neural conduction
Neural Pathways
Prefrontal cortex
Prefrontal Cortex - physiology
Psychological Patterns
Psychological Studies
Reviews
Serotonin - physiology
Stimuli
Violence
Violence research
title Dysfunction in the Neural Circuitry of Emotion Regulation: A Possible Prelude to Violence
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